A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function
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Phylogenetic framework and molecular signatures for the main clades of the phylum Actinobacteria.Structural insights into quinolone antibiotic resistance mediated by pentapeptide repeat proteins: conserved surface loops direct the activity of a Qnr protein from a Gram-negative bacteriumThe Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA CleavageMechanisms for Defining Supercoiling Set Point of DNA Gyrase Orthologs: II. THE SHAPE OF THE GyrA SUBUNIT C-TERMINAL DOMAIN (CTD) IS NOT A SOLE DETERMINANT FOR CONTROLLING SUPERCOILING EFFICIENCYDirect control of type IIA topoisomerase activity by a chromosomally encoded regulatory proteinProtein based molecular markers provide reliable means to understand prokaryotic phylogeny and support Darwinian mode of evolutionFluoroquinolone-gyrase-DNA complexes: two modes of drug binding.Phylogeny and molecular signatures for the phylum Thermotogae and its subgroups.Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.High confidence prediction of essential genes in Burkholderia cenocepacia.Bypassing fluoroquinolone resistance with quinazolinediones: studies of drug-gyrase-DNA complexes having implications for drug design.N-Benzyl-3-sulfonamidopyrrolidines are a New Class of Bacterial DNA Gyrase Inhibitors.DNA-induced narrowing of the gyrase N-gate coordinates T-segment capture and strand passageGuiding strand passage: DNA-induced movement of the gyrase C-terminal domains defines an early step in the supercoiling cycleE. coli Gyrase Fails to Negatively Supercoil Diaminopurine-Substituted DNA.Interactions between QnrB, QnrB mutants, and DNA gyrase.Functional Analyses of the Toxoplasma gondii DNA Gyrase Holoenzyme: A Janus Topoisomerase with Supercoiling and Decatenation Abilities.The GyrA-box determines the geometry of DNA bound to gyrase and couples DNA binding to the nucleotide cycle.Structural insight into negative DNA supercoiling by DNA gyrase, a bacterial type 2A DNA topoisomeraseAntibacterial small molecules targeting the conserved TOPRIM domain of DNA gyrase.Structural basis of DNA gyrase inhibition by antibacterial QPT-1, anticancer drug etoposide and moxifloxacin.Ribonucleotide Reductases from Bifidobacteria Contain Multiple Conserved Indels Distinguishing Them from All Other Organisms: In Silico Analysis of the Possible Role of a 43 aa Bifidobacteria-Specific Insert in the Class III RNR Homolog.DNA gyrase with a single catalytic tyrosine can catalyze DNA supercoiling by a nicking-closing mechanism.ATP binding controls distinct structural transitions of Escherichia coli DNA gyrase in complex with DNA.Phylogenetic analysis and molecular signatures defining a monophyletic clade of heterocystous cyanobacteria and identifying its closest relatives.Fluoroquinolone-Gyrase-DNA Cleaved Complexes.Novel Sequence Features of DNA Repair Genes/Proteins from Deinococcus Species Implicated in Protection from Oxidatively Generated Damage.Phylogenomics and Comparative Genomic Studies Robustly Support Division of the Genus Mycobacterium into an Emended Genus Mycobacterium and Four Novel Genera.
P2860
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P2860
A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function
description
2010 nî lūn-bûn
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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A domain insertion in Escheric ...... itical role in gyrase function
@ast
A domain insertion in Escheric ...... itical role in gyrase function
@en
A domain insertion in Escheric ...... itical role in gyrase function
@nl
type
label
A domain insertion in Escheric ...... itical role in gyrase function
@ast
A domain insertion in Escheric ...... itical role in gyrase function
@en
A domain insertion in Escheric ...... itical role in gyrase function
@nl
prefLabel
A domain insertion in Escheric ...... itical role in gyrase function
@ast
A domain insertion in Escheric ...... itical role in gyrase function
@en
A domain insertion in Escheric ...... itical role in gyrase function
@nl
P2093
P2860
P3181
P356
P1476
A domain insertion in Escheric ...... itical role in gyrase function
@en
P2093
Allyn J Schoeffler
Andrew P May
James M Berger
P2860
P304
P3181
P356
10.1093/NAR/GKQ665
P407
P577
2010-11-01T00:00:00Z