Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1 - Wikidata - wikimedia - TriplyDB

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

http://www.wikidata.org/entity/Q27664073

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Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complex The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases Molecular basis for DPY-30 association to COMPASS-like and NURF complexes Structural basis for activity regulation of MLL family methyltransferases The MYC-WDR5 Nexus and Cancer The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2 Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain A non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexes Fluorescence-based methods for screening writers and readers of histone methyl marks.Perspectives on the discovery of small-molecule modulators for epigenetic processes.Substrate and product specificities of SET domain methyltransferases WRAD: enabler of the SET1-family of H3K4 methyltransferases.ATX1-generated H3K4me3 is required for efficient elongation of transcription, not initiation, at ATX1-regulated genes A phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.WD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human.Charge-based interaction conserved within histone H3 lysine 4 (H3K4) methyltransferase complexes is needed for protein stability, histone methylation, and gene expression Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency.The role of maintenance proteins in the preservation of epithelial cell identity during mammary gland remodeling and breast cancer initiation.SET for life: biochemical activities and biological functions of SET domain-containing proteins PI3K/AKT-mediated upregulation of WDR5 promotes colorectal cancer metastasis by directly targeting ZNF407.Every methyl counts--epigenetic calculus.The many facets of MLL1 regulation.Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.An Embryonic Stem Cell-Specific NuRD Complex Functions through Interaction with WDR5.Targeting human SET1/MLL family of proteins.Diverse roles of WDR5-RbBP5-ASH2L-DPY30 (WRAD) complex in the functions of the SET1 histone methyltransferase family.Evolving Catalytic Properties of the MLL Family SET Domain.Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5 Assembling a COMPASS.Upon Infection the Cellular WD Repeat-containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication.Bivalent Epigenetic Control of Oncofetal Gene Expression in Cancer.Moonlighting with WDR5: A Cellular Multitasker.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.

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P2860

Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1

http://www.wikidata.org/entity/Q27664073

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Journal of Biological Chemistry

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Characterization of a Novel WD ...... xed Lineage Leukemia Protein-1

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Stacey M Southall

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Zain Odho

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P2860

Subunit composition and substrate specificity of a MOF-containing histone acetyltransferase distinct from the male-specific lethal (MSL) complex

Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8

Structural basis for molecular recognition and presentation of histone H3 by WDR5

eIF4A3 is a novel component of the exon junction complex

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5

CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes

WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket

Structural basis for the requirement of additional factors for MLL1 SET domain activity and recognition of epigenetic marks

The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

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