Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21 - Wikidata - wikimedia - TriplyDB

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

http://www.wikidata.org/entity/Q27667261

about

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis Substrate specificity of the ubiquitin and Ubl proteases Optimising methods for the preservation, capture and identification of ubiquitin chains and ubiquitylated proteins by immunoblotting A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity Assembly, analysis and architecture of atypical ubiquitin chains Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease New conformations of linear polyubiquitin chains from crystallographic and solution-scattering studies expand the conformational space of polyubiquitin Genetically Directed Production of Recombinant, Isosteric and Nonhydrolysable Ubiquitin Conjugates Molecular basis for specificity of the Met1-linked polyubiquitin signal Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20 Ubiquitin chain conformation regulates recognition and activity of interacting proteins Complex structure of OspI and Ubc13: the molecular basis of Ubc13 deamidation and convergence of bacterial and host E2 recognition Molecular characterization of ubiquitin-specific protease 18 reveals substrate specificity for interferon-stimulated gene 15 Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase The molecular determinants for distinguishing between ubiquitin and NEDD8 by USP2.Protein neddylation: beyond cullin-RING ligases.Deubiquitination and stabilization of IL-33 by USP21.Selective inactivation of USP18 isopeptidase activity in vivo enhances ISG15 conjugation and viral resistance Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation Protein-linked ubiquitin chain structure restricts activity of deubiquitinating enzymes.Evolutionary Loss of Activity in De-Ubiquitylating Enzymes of the OTU Family.Deubiquitinases in cancer.HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.Recognition and cleavage of related to ubiquitin 1 (Rub1) and Rub1-ubiquitin chains by components of the ubiquitin-proteasome system An Ubiquitin-like Motif in ASK1 Mediates its Association with and Inhibition of the Proteasome.The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog.The WD40-repeat protein-containing deubiquitinase complex: catalysis, regulation, and potential for therapeutic intervention.USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.Regulation of proteolysis by human deubiquitinating enzymes.Deubiquitylases from genes to organism.Data driven flexible backbone protein design.Activity-Based Probes for HECT E3 Ubiquitin Ligases CRL2Lrr1 promotes unloading of the vertebrate replisome from chromatin during replication termination.USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma.Structural basis of the specificity of USP18 toward ISG15.

P2860

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P2860

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

http://www.wikidata.org/entity/Q27667261

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@ast

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@en

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@nl

type

label

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@ast

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@en

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@nl

prefLabel

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@ast

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@en

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@nl

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P1476

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

@en

P2093

Francisca Reyes-Turcu

http://www.w3.org/2001/XMLSchema#string

Keith D Wilkinson

http://www.w3.org/2001/XMLSchema#string

Masato Akutsu

http://www.w3.org/2001/XMLSchema#string

Radoslav I Enchev

http://www.w3.org/2001/XMLSchema#string

Yu Ye

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins

Defining the human deubiquitinating enzyme interaction landscape

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes

Origin and function of ubiquitin-like proteins

Structure of ubiquitin refined at 1.8 A resolution

UBP43 (USP18) specifically removes ISG15 from conjugated proteins.

Breaking the chains: structure and function of the deubiquitinases

Dissection of USP catalytic domains reveals five common insertion points

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350-7

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scholarly article

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2449696

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10.1038/EMBOR.2011.17

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4

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12

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21399617

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3077245

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