CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration
about
IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradationStructural basis for autoinhibition and phosphorylation-dependent activation of c-CblInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationSmall-molecule SMAC mimetics as new cancer therapeuticsIAPs: a central element in the NF-κB activating signaling pathwayStructure of a Glomulin-RBX1-CUL1 Complex: Inhibition of a RING E3 Ligase through Masking of Its E2-Binding SurfaceStructural Insight into Inhibitor of Apoptosis Proteins Recognition by a Potent Divalent Smac-MimeticStructure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation MechanismThe structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidizedInducing death in tumor cells: roles of the inhibitor of apoptosis proteins.The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylationNuclear factor-κB-inducing kinase (NIK) contains an amino-terminal inhibitor of apoptosis (IAP)-binding motif (IBM) that potentiates NIK degradation by cellular IAP1 (c-IAP1).HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerizationAminomethylphosphonic acid and methoxyacetic acid induce apoptosis in prostate cancer cells.Inhibitor of apoptosis proteins as intracellular signaling intermediates.Itch WW Domains Inhibit Its E3 Ubiquitin Ligase Activity by Blocking E2-E3 Ligase Trans-thiolation.Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells.Structural basis of signal transduction in the TNF receptor superfamilySmac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity.The Inhibitor of Apoptosis (IAPs) in Adaptive Response to Cellular StressRegulation of Apoptosis by Inhibitors of Apoptosis (IAPs)IAPs: guardians of RIPK1IAPS and ubiquitylation.Zinc-rich inhibitor of apoptosis proteins (IAPs) as regulatory factors in the epithelium of normal and inflamed airways.Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists.IAPs on the move: role of inhibitors of apoptosis proteins in cell migration.The versatile roles of CARDs in regulating apoptosis, inflammation, and NF-κB signaling.Structural insights into the catalysis and regulation of E3 ubiquitin ligases.Impact of inhibitor of apoptosis proteins on immune modulation and inflammation.Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins.cIAP1/2 negatively regulate RANKL-induced osteoclastogenesis through the inhibition of NFATc1 expression.Vinculin functions as regulator of chondrogenesisUbiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray.Internal motions prime cIAP1 for rapid activation.IAPs as E3 ligases of Rac1: shaping the move.Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner.cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation.Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation.Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.Inhibitors of apoptosis: clinical implications in cancer.
P2860
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P2860
CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
CARD-mediated autoinhibition o ...... ll proliferation and migration
@ast
CARD-mediated autoinhibition o ...... ll proliferation and migration
@en
CARD-mediated autoinhibition o ...... ll proliferation and migration
@nl
type
label
CARD-mediated autoinhibition o ...... ll proliferation and migration
@ast
CARD-mediated autoinhibition o ...... ll proliferation and migration
@en
CARD-mediated autoinhibition o ...... ll proliferation and migration
@nl
prefLabel
CARD-mediated autoinhibition o ...... ll proliferation and migration
@ast
CARD-mediated autoinhibition o ...... ll proliferation and migration
@en
CARD-mediated autoinhibition o ...... ll proliferation and migration
@nl
P2093
P50
P1433
P1476
CARD-mediated autoinhibition o ...... ll proliferation and migration
@en
P2093
Floriana Francalanci
Gilles J P Rautureau
Juanita Lopez
Mark G Hinds
Meike Broemer
Rebecca Wilson
Sidonie Wicky John
Tencho Tenev
P304
P356
10.1016/J.MOLCEL.2011.04.008
P577
2011-06-10T00:00:00Z