Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase - Wikidata - wikimedia - TriplyDB

Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase

Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase

http://www.wikidata.org/entity/Q27667828

about

Active site opening and closure control translocation of multisubunit RNA polymerase Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase.Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β.Engineering processive DNA polymerases with maximum benefit at minimum cost Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.Direct observation of translocation in individual DNA polymerase complexes.TP-RT domain interactions of duck hepatitis B virus reverse transcriptase in cis and in trans during protein-primed initiation of DNA synthesis in vitro.Herpes simplex viruses: mechanisms of DNA replication.Protein-primed terminal transferase activity of hepatitis B virus polymerase.Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer.Pronounced Inhibition Shift from HIV Reverse Transcriptase to Herpetic DNA Polymerases by Increasing the Flexibility of α-Carboxy Nucleoside Phosphonates.Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase Utility of the bacteriophage RB69 polymerase gp43 as a surrogate enzyme for herpesvirus orthologs.Impact of primer-induced conformational dynamics of HIV-1 reverse transcriptase on polymerase translocation and inhibition.Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus.Foscarnet resistance mutations mapping to atypical domains of the cytomegalovirus DNA polymerase gene.Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase.The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.Conjugation of phosphonoacetic acid to nucleobase promotes a mechanism-based inhibition.DNA synthesis from diphosphate substrates by DNA polymerases.

P2860

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P2860

Phosphonoformic Acid Inhibits Viral Replication by Trapping the Closed Form of the DNA Polymerase

http://www.wikidata.org/entity/Q27667828

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

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2011年论文

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name

Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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JBC.M111.248864

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Journal of Biological Chemistry

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Phosphonoformic Acid Inhibits ...... sed Form of the DNA Polymerase

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Egor P Tchesnokov

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Karl E Zahn

http://www.w3.org/2001/XMLSchema#string

Matthias Götte

http://www.w3.org/2001/XMLSchema#string

P2860

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases

Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet.

MUSCLE: multiple sequence alignment with high accuracy and high throughput

Processing of X-ray diffraction data collected in oscillation mode

Structure of the replicating complex of a pol alpha family DNA polymerase

Role of the catalytic metal during polymerization by DNA polymerase lambda

Caught bending the A-rule: crystal structures of translesion DNA synthesis with a non-natural nucleotide

Kinetics of Mismatch Formation opposite Lesions by the Replicative DNA Polymerase from Bacteriophage RB69

Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

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scholarly article

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4761126

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10.1074/JBC.M111.248864

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28

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286

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Sylvie Doublié

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2011-07-15T00:00:00Z

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51120916

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21566148

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viral replication

P932

3137095

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