Active site opening and closure control translocation of multisubunit RNA polymerase
about
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.Response to Klyuyev and Vassylyev: on the mechanism of tagetitoxin inhibition of transcriptionBridge helix bending promotes RNA polymerase II backtracking through a critical and conserved threonine residueBacterial RNA Polymerase-DNA Interaction-The Driving Force of Gene Expression and the Target for Drug ActionMillisecond dynamics of RNA polymerase II translocation at atomic resolutionUnveiling translocation intermediates of RNA polymeraseTranslocation and fidelity of Escherichia coli RNA polymeraseColiphage HK022 Nun protein inhibits RNA polymerase translocationRNA polymerase pausing and nascent-RNA structure formation are linked through clamp-domain movementTranscription elongation. Heterogeneous tracking of RNA polymerase and its biological implications.Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase.CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.Transient-State Kinetic Analysis of the RNA Polymerase I Nucleotide Incorporation Mechanism.Bacterial Transcription as a Target for Antibacterial Drug Development.The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.RNA polymerase stalls in a post-translocated register and can hyper-translocate.Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.Functional interplay between NTP leaving group and base pair recognition during RNA polymerase II nucleotide incorporation revealed by methylene substitutionComplete dissection of transcription elongation reveals slow translocation of RNA polymerase II in a linear ratchet mechanismComputational simulation strategies for analysis of multisubunit RNA polymerases.Interplay between the trigger loop and the F loop during RNA polymerase catalysis.Antisense oligonucleotide-stimulated transcriptional pausing reveals RNA exit channel specificity of RNA polymerase and mechanistic contributions of NusA and RfaH.CBR antimicrobials alter coupling between the bridge helix and the β subunit in RNA polymerase.A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket.Basic mechanism of transcription by RNA polymerase II.Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases.Regulation of Transcript Elongation.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.Rate-limiting Pyrophosphate Release by HIV Reverse Transcriptase Improves Fidelity.Cys-pair reporters detect a constrained trigger loop in a paused RNA polymerase.A structure-based kinetic model of transcription.NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubbleThe RNA polymerase trigger loop functions in all three phases of the transcription cycle.Tagetitoxin inhibits transcription by stabilizing pre-translocated state of the elongation complex.Pyrophosphate Release in the Protein HIV Reverse Transcriptase.Dynamics of bridge helix bending in RNA polymerase II.
P2860
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P2860
Active site opening and closure control translocation of multisubunit RNA polymerase
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Active site opening and closure control translocation of multisubunit RNA polymerase
@ast
Active site opening and closure control translocation of multisubunit RNA polymerase
@en
Active site opening and closure control translocation of multisubunit RNA polymerase
@nl
type
label
Active site opening and closure control translocation of multisubunit RNA polymerase
@ast
Active site opening and closure control translocation of multisubunit RNA polymerase
@en
Active site opening and closure control translocation of multisubunit RNA polymerase
@nl
prefLabel
Active site opening and closure control translocation of multisubunit RNA polymerase
@ast
Active site opening and closure control translocation of multisubunit RNA polymerase
@en
Active site opening and closure control translocation of multisubunit RNA polymerase
@nl
P2093
P2860
P50
P3181
P356
P1476
Active site opening and closure control translocation of multisubunit RNA polymerase
@en
P2093
Lioudmila Vainonen
Marimuthu Parthiban
Mark S Johnson
P2860
P304
P3181
P356
10.1093/NAR/GKS383
P407
P577
2012-05-08T00:00:00Z