Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor
about
Graphene oxide attenuates Th2-type immune responses, but augments airway remodeling and hyperresponsiveness in a murine model of asthmaHuman YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding propertiesMacrophage proliferation, provenance, and plasticity in macroparasite infectionStructural characteristics of an insect group I chitinase, an enzyme indispensable to moultingModification and periplasmic translocation of the biofilm exopolysaccharide poly- -1,6-N-acetyl-D-glucosamineScreening-based discovery ofAspergillus fumigatusplant-type chitinase inhibitorsProtein A-mouse acidic mammalian chitinase-V5-His expressed in periplasmic space of Escherichia coli possesses chitinase functions comparable to CHO-expressed protein.Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage.Expression of YKL-40 and MIP-1a proteins in exudates and transudates: biomarkers for differential diagnosis of pleural effusions? A pilot study.Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.Chitinolytic enzymes: an appraisal as a product of commercial potential.Structure, Catalysis, and Inhibition of OfChi-h, the Lepidoptera-exclusive Insect Chitinase.Suppression of type 2 immunity and allergic airway inflammation by secreted products of the helminth Heligmosomoides polygyrus.Functional properties of the catalytic domain of mouse acidic mammalian chitinase expressed in Escherichia coli.How to target small cell lung cancer.New paralogues and revised time line in the expansion of the vertebrate GH18 family.The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile.Mouse acidic mammalian chitinase exhibits transglycosylation activity at somatic tissue pH.PgaB orthologues contain a glycoside hydrolase domain that cleaves deacetylated poly-β(1,6)-N-acetylglucosamine and can disrupt bacterial biofilms.
P2860
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P2860
Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@ast
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@en
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@nl
type
label
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@ast
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@en
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@nl
prefLabel
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@ast
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@en
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@nl
P2860
P50
P921
P1476
Analyzing Airway Inflammation ...... Selective Drug-like Inhibitor
@en
P2093
Marie Betou
Rick M Maizels
P2860
P304
P356
10.1016/J.CHEMBIOL.2011.02.017
P577
2011-05-27T00:00:00Z