about
Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding propertiesThe cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediateStructure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor ArgifinNatural Product–Guided Discovery of a Fungal Chitinase InhibitorStructural features and ligand binding properties of tandem WW domains from YAP and TAZ, nuclear effectors of the Hippo pathwayAnalyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like InhibitorThe cancer chemopreventive actions of phytochemicals derived from glucosinolatesOriented immobilisation of engineered single-chain antibodies to develop biosensors for virus detection.5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy.Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism.Bisdionin C-a rationally designed, submicromolar inhibitor of family 18 chitinasesEffective photoinactivation of Gram-positive and Gram-negative bacterial strains using an HIV-1 Tat peptide-porphyrin conjugate.Photochemical internalisation of a macromolecular protein toxin using a cell penetrating peptide-photosensitiser conjugate.Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme.Structural insights into the mechanism and inhibition of eukaryotic O-GlcNAc hydrolysisFluorescence lifetime imaging and FRET-induced intracellular redistribution of Tat-conjugated quantum dot nanoparticles through interaction with a phthalocyanine photosensitiser.Natural product family 18 chitinase inhibitors.Skin protection against UVA-induced iron damage by multiantioxidants and iron chelating drugs/prodrugs.A fluorescent Arg-Gly-Asp (RGD) peptide-naphthalenediimide (NDI) conjugate for imaging integrin α(v)β(3) in vitro.The use of dipeptide derivatives of 5-aminolaevulinic acid promotes their entry to tumor cells and improves tumor selectivity of photodynamic therapy.Time-dependent inhibitors of trypanothione reductase: analogues of the spermidine alkaloid lunarine and related natural products.Flexible synthesis of cationic peptide-porphyrin derivatives for light-triggered drug delivery and photodynamic therapy.Improved peptide prodrugs of 5-ALA for PDT: rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization.Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines.Enhanced paracellular transport of insulin can be achieved via transient induction of myosin light chain phosphorylation.Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase.Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold.Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase.Structure-based exploration of cyclic dipeptide chitinase inhibitors.1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic alpha,beta-unsaturated aldehyde acrolein.Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.A novel flow cytometry assay using dihydroethidium as redox-sensitive probe reveals NADPH oxidase-dependent generation of superoxide anion in human platelets exposed to amyloid peptide β.An efficient synthesis of argifin: a natural product chitinase inhibitor with chemotherapeutic potential.Screening-based discovery and structural dissection of a novel family 18 chitinase inhibitor.Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation in polarized intestinal epithelia.Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acidChemical approaches for the enhancement of 5-aminolevulinic acid-based photodynamic therapy and photodiagnosisCodelivery of a cytotoxin and photosensitiser via a liposomal nanocarrier: a novel strategy for light-triggered cytosolic releaseTotal Synthesis of Dolatrienoic Acid: A Subunit of Dolastatin 14Development of a peptide-based fluorescent probe for biological heme monitoring
P50
Q24339271-092A38E1-14FC-42F1-A1DE-48A3791429F7Q27639704-CC68FDEF-3517-46CC-BCA8-E16AC336BE75Q27650124-8DADDEF8-AD32-4767-964B-0AE4853C4CBFQ27666337-F1BE0C41-77CB-4746-8ACB-3D5B3584F054Q27667018-0BFE676F-9AC5-4D66-A2E8-68207ADBC2FFQ27667980-0A714ED5-5295-4F18-B96C-F96B7F87B715Q28279051-FA52C853-2FA7-4B11-AAEB-9666340FFB73Q33232216-41A399A7-E794-4E50-B41B-00F3E29794A6Q33345156-09908F15-9447-48FB-BBF1-5B824EA072FAQ33412105-88FC98C3-2584-476A-9446-008246201857Q33598650-2ABAA814-02AD-461B-BC7D-B801F1D6D8E5Q33712810-F61D39E8-E1F1-4648-BBCC-8448AFCAF2CCQ34010471-C0D7E0C5-167C-4156-ACD4-A4C0FC2CA2E2Q34487152-B4ABB9C2-342F-4C48-9520-F3F2832A0874Q34502637-B660EE8B-A476-40D9-A204-9D46936E5A38Q34986288-6BEF2E87-9927-4601-8F56-6DE023A0DF8AQ36271779-128CBA29-0A28-4EAA-8723-2E3047B89B42Q37734519-FF9A7C88-C835-4580-9A8A-A0AC0478EB37Q38913470-C078AB62-1FC2-4312-834F-2A5BF596FCDFQ38927596-84180253-7E0F-42D7-B640-8BCFC872C4D6Q39043147-2F5A62A5-E487-4EAA-9652-8F27007741CAQ39314880-E9180834-2618-44F6-87C6-F6492EA09F1AQ39843341-8870C78D-9FD4-47EB-A45B-55A48B7D5617Q41075146-F0B95284-0A42-483C-B903-E5A175ED325BQ41710814-2957CA0F-8EE7-487F-A658-544CB5F2460CQ41790538-9E16D7C2-EB49-4B44-B480-09DA9599552FQ43160805-99401412-F58C-427D-9DA1-172B1D9AC0C3Q44539049-ED622DEA-D9AA-41F9-B395-1C29BF088FA5Q45127571-EEA34ED1-3EB1-4E27-85F7-E559CA94557AQ45919580-44704124-8CE4-4B1C-A858-F63251ED9CE6Q46079650-13DC78F5-5381-4EE6-9586-39A0D3677ED1Q46247855-A9C79C7B-AE2A-437B-92D7-F946A3AE90E6Q46695588-6680769F-05B1-4161-8DBB-0A256D4B89B7Q51937592-26E7B9AD-58E2-4B18-A0FF-4404129BBDF6Q52610072-A10BDDA9-0F0B-4AE4-96F5-F6F08BDCD004Q57359712-5D5A094A-A16B-4FA3-9308-7E3BF5C0056EQ57454431-456B7DC4-D48F-441D-999E-86863C13218CQ58097539-E1771497-00C1-4BA5-8E05-84C102DC38A7Q74836437-26BCD680-BD17-495F-AE51-F2FF791A798CQ90689136-D469AEB2-B63C-4E13-92E7-709E4381DBEA
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
I Eggleston
@ast
I Eggleston
@en
I Eggleston
@es
I Eggleston
@nl
I Eggleston
@sl
type
label
I Eggleston
@ast
I Eggleston
@en
I Eggleston
@es
I Eggleston
@nl
I Eggleston
@sl
prefLabel
I Eggleston
@ast
I Eggleston
@en
I Eggleston
@es
I Eggleston
@nl
I Eggleston
@sl
P106
P1153
56013223800
P31
P496
0000-0003-0569-0082