Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
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Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10Antibody promiscuity: Understanding the paradigm shift in antigen recognitionB Cells and Functional Antibody Responses to Combat InfluenzaStructural characterization of viral epitopes recognized by broadly cross-reactive antibodiesStructural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibodyHuman antibodies that neutralize respiratory droplet transmissible H5N1 influenza virusesAntibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding SiteAutoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10A common solution to group 2 influenza virus neutralizationReceptor mimicry by antibody F045–092 facilitates universal binding to the H3 subtype of influenza virusAlternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a VH3-30-Encoded Heterosubtypic AntibodyConserved Neutralizing Epitope at Globular Head of Hemagglutinin in H3N2 Influenza VirusesAffinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domainsSomatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing AntibodiesInfluenza hemagglutinin stem-fragment immunogen elicits broadly neutralizing antibodies and confers heterologous protectionLarge-scale analysis of B-cell epitopes on influenza virus hemagglutinin - implications for cross-reactivity of neutralizing antibodies.Immunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.The Analysis of B-Cell Epitopes of Influenza Virus Hemagglutinin.Influenza immunization elicits antibodies specific for an egg-adapted vaccine strainEmerging antiviral strategies to interfere with influenza virus entry.Redesigned HIV antibodies exhibit enhanced neutralizing potency and breadth.Characterization of a broadly neutralizing monoclonal antibody that targets the fusion domain of group 2 influenza A virus hemagglutinin.Human germline antibody gene segments encode polyspecific antibodies.Development of scoring functions for antibody sequence assessment and optimization.Structure of the apo anti-influenza CH65 Fab.Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved.Overlapping hotspots in CDRs are critical sites for V region diversificationStructural basis for Marburg virus neutralization by a cross-reactive human antibody.Broad blockade antibody responses in human volunteers after immunization with a multivalent norovirus VLP candidate vaccine: immunological analyses from a phase I clinical trialOptMAVEn--a new framework for the de novo design of antibody variable region models targeting specific antigen epitopes.Influenza virus antigenicity and broadly neutralizing epitopes.Increased Fab thermoresistance via VH-targeted directed evolution.Discovering neutralizing antibodies targeting the stem epitope of H1N1 influenza hemagglutinin with synthetic phage-displayed antibody libraries.Inhibitory Effect of Individual or Combinations of Broadly Neutralizing Antibodies and Antiviral Reagents against Cell-Free and Cell-to-Cell HIV-1 Transmission.Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites.Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virusComplex Antigens Drive Permissive Clonal Selection in Germinal Centers.Characterization of pathogenic human monoclonal autoantibodies against GM-CSF.Large-scale sequence and structural comparisons of human naive and antigen-experienced antibody repertoires.Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
P2860
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P2860
Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Preconfiguration of the antige ...... izing influenza virus antibody
@nl
Preconfiguration of the antige ...... zing influenza virus antibody.
@ast
Preconfiguration of the antige ...... zing influenza virus antibody.
@en
type
label
Preconfiguration of the antige ...... izing influenza virus antibody
@nl
Preconfiguration of the antige ...... zing influenza virus antibody.
@ast
Preconfiguration of the antige ...... zing influenza virus antibody.
@en
prefLabel
Preconfiguration of the antige ...... izing influenza virus antibody
@nl
Preconfiguration of the antige ...... zing influenza virus antibody.
@ast
Preconfiguration of the antige ...... zing influenza virus antibody.
@en
P2093
P2860
P50
P3181
P356
P1476
Preconfiguration of the antige ...... zing influenza virus antibody.
@en
P2093
Aaron G Schmidt
Andrea Carfi
David E Shaw
Ethan C Settembre
Hana Golding
Hua-Xin Liao
Huafeng Xu
Jody Manischewitz
Lisa R King
M Anthony Moody
P2860
P304
P3181
P356
10.1073/PNAS.1218256109
P407
P577
2012-11-21T00:00:00Z