Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
about
Structural and molecular basis for Ebola virus neutralization by protective human antibodiesSomatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing AntibodiesImmunogenic Stimulus for Germline Precursors of Antibodies that Engage the Influenza Hemagglutinin Receptor-Binding Site.ABodyBuilder: Automated antibody structure prediction with data-driven accuracy estimation.HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Vaccine-induced plasmablast responses in rhesus macaques: phenotypic characterization and a source for generating antigen-specific monoclonal antibodies.Strategies to guide the antibody affinity maturation processDynamics of immunoglobulin sequence diversity in HIV-1 infected individuals.Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants.HIV Vaccine: Recent Advances, Current Roadblocks, and Future Directions.Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.Conformational Epitope-Specific Broadly Neutralizing Plasma Antibodies Obtained from an HIV-1 Clade C-Infected Elite Neutralizer Mediate Autologous Virus Escape through Mutations in the V1 Loop.Structural basis for germline antibody recognition of HIV-1 immunogens.HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds.Native-like Env trimers as a platform for HIV-1 vaccine design.Genetic and structural analyses of affinity maturation in the humoral response to HIV-1.Polyvalent vaccine approaches to combat HIV-1 diversityStaged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo.Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing.Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies.Computational Tools for Aiding Rational Antibody Design.HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.Structural Insights from HIV-Antibody Coevolution and Related Immunization Studies
P2860
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P2860
Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Affinity maturation in an HIV ...... rientation of variable domains
@ast
Affinity maturation in an HIV ...... rientation of variable domains
@en
Affinity maturation in an HIV ...... rientation of variable domains
@nl
type
label
Affinity maturation in an HIV ...... rientation of variable domains
@ast
Affinity maturation in an HIV ...... rientation of variable domains
@en
Affinity maturation in an HIV ...... rientation of variable domains
@nl
prefLabel
Affinity maturation in an HIV ...... rientation of variable domains
@ast
Affinity maturation in an HIV ...... rientation of variable domains
@en
Affinity maturation in an HIV ...... rientation of variable domains
@nl
P2093
P2860
P3181
P356
P1476
Affinity maturation in an HIV ...... rientation of variable domains
@en
P2093
Aaron G Schmidt
Hua-Xin Liao
Stephen C Harrison
Thomas B Kepler
P2860
P304
P3181
P356
10.1073/PNAS.1409954111
P407
P577
2014-07-15T00:00:00Z