IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
about
p38γ and p38δ Mitogen Activated Protein Kinases (MAPKs), New Stars in the MAPK GalaxyNovel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway DiseasesLinking acute infection to chronic lung disease. The role of IL-33-expressing epithelial progenitor cellsIL-4 and IL-13 signaling in allergic airway diseaseThe cell biology of asthmaPathogens penetrating the central nervous system: infection pathways and the cellular and molecular mechanisms of invasionRespiratory epithelial cells orchestrate pulmonary innate immunity.Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formationA computational strategy to select optimized protein targets for drug development toward the control of cancer diseasesStructural insights into the polypharmacological activity of quercetin on serine/threonine kinasesComparative chemical array screening for p38γ/δ MAPK inhibitors using a single gatekeeper residue difference between p38α/β and p38γ/δInfluence of sex and disease severity on gene expression profiles in individuals with idiopathic pulmonary fibrosis.Chemosensory functions for pulmonary neuroendocrine cellsmCLCA3 modulates IL-17 and CXCL-1 induction and leukocyte recruitment in murine Staphylococcus aureus pneumonia.Myb permits multilineage airway epithelial cell differentiation.Interferon response and respiratory virus control are preserved in bronchial epithelial cells in asthma.High-throughput screening normalized to biological response: application to antiviral drug discovery.Murine CLCA5 is uniquely expressed in distinct niches of airway epithelial cells.The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.Secreted CLCA1 modulates TMEM16A to activate Ca(2+)-dependent chloride currents in human cells.Interleukin-17A promotes MUC5AC expression and goblet cell hyperplasia in nasal polyps via the Act1-mediated pathway.TREM-2 promotes macrophage survival and lung disease after respiratory viral infectionThe Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation.The role of airway epithelial cells and innate immune cells in chronic respiratory disease.LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium.IL13 activates autophagy to regulate secretion in airway epithelial cellsLong-term IL-33-producing epithelial progenitor cells in chronic obstructive lung disease.Identifying core herbal treatments for children with asthma: implication from a chinese herbal medicine database in taiwan.Regulated mucin secretion from airway epithelial cellsLyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma.Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma.p38δ MAPK: Emerging Roles of a Neglected IsoformRole of goblet cell protein CLCA1 in murine DSS colitisCLCA1 and TMEM16A: the link towards a potential cure for airway diseases.Modulation of TMEM16A channel activity by the von Willebrand factor type A (VWA) domain of the calcium-activated chloride channel regulator 1 (CLCA1).First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.Secreted hCLCA1 is a signaling molecule that activates airway macrophages.The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation.Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells
P2860
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P2860
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
description
2012 nî lūn-bûn
@nan
2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@ast
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@en
IL-13–induced airway mucus production is attenuated by MAPK13 inhibition
@nl
type
label
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@ast
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@en
IL-13–induced airway mucus production is attenuated by MAPK13 inhibition
@nl
prefLabel
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@ast
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@en
IL-13–induced airway mucus production is attenuated by MAPK13 inhibition
@nl
P2093
P2860
P3181
P356
P1476
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
@en
P2093
Anand C Patel
Arthur G Romero
Chantel A Miller
Dhara A Patel
Jennifer Tucker
Richard F Heier
Tom J Brett
William T Roswit
Yael G Alevy
P2860
P304
P3181
P356
10.1172/JCI64896
P407
P577
2012-11-26T00:00:00Z