The polymeric mucin Muc5ac is required for allergic airway hyperreactivity. - Wikidata - wikimedia - TriplyDB

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

http://www.wikidata.org/entity/Q35098892

about

IL-4 and IL-13 signaling in allergic airway disease Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99 Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.SNAP23 is selectively expressed in airway secretory cells and mediates baseline and stimulated mucin secretion.MicroRNAs 24 and 27 Suppress Allergic Inflammation and Target a Network of Regulators of T Helper 2 Cell-Associated Cytokine Production Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma T cells suppress memory-dependent rapid mucous cell metaplasia in mouse airways.DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma.Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma.Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation.Gastric Proteins MUC5AC and TFF1 as Potential Diagnostic Markers of Colonic Sessile Serrated Adenomas/Polyps.Airway remodelling and inflammation in asthma are dependent on the extracellular matrix protein fibulin-1c.MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.Rho-kinase inhibitor fasudil reduces allergic airway inflammation and mucus hypersecretion by regulating STAT6 and NFκB.Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases.Allergic airway inflammation: key players beyond the Th2 cell pathway.MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma.Identification of Epithelial Phospholipase A2 Receptor 1 as a Potential Target in Asthma.T cells are the critical source of IL-4/IL-13 in a mouse model of allergic asthma.Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice.Both Ways at Once: Keeping Small Airways Clean.Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.Secreted PLA2 group X orchestrates innate and adaptive immune responses to inhaled allergen.Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice.Identification of trans Protein QTL for Secreted Airway Mucins in Mice and a Causal Role for Bpifb1.Update in Asthma 2016.Airway Mucus and Asthma: The Role of MUC5AC and MUC5B.ATP12A promotes mucus dysfunction during Type 2 airway inflammation.Infection is Not Required for Mucoinflammatory Lung Disease in CFTR-knockout Ferrets.Ramifications of Secreted Mucin MUC5AC in Malignant Journey: A Holistic View.All plugged up - noninvasive mucus score to assess airway dysfunction in asthma.Etiology of epithelial barrier dysfunction in patients with type 2 inflammatory diseases.IκBNS induces Muc5ac expression in epithelial cells and causes airway hyper-responsiveness in murine asthma models.CD34 Differentially Regulates Contractile and Noncontractile Elements of Airway Reactivity.SPDEFending the Lung through Mucin Expression.Electronic cigarettes: One size does not fit all.Low Dose Carbon Black Nanoparticle Exposure Does Not Aggravate Allergic Airway Inflammation in Mice Irrespective of the Presence of Surface Polycyclic Aromatic Hydrocarbons.Platelet Munc13-4 regulates hemostasis, thrombosis and airway inflammation.

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The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

http://www.wikidata.org/entity/Q35098892

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

name

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@ast

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@en

type

label

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@ast

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@en

prefLabel

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@ast

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@en

P1433

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P1433

Nature Communications

P1476

The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.

@en

P2093

Ashley A Fletcher

http://www.w3.org/2001/XMLSchema#string

Burton F Dickey

http://www.w3.org/2001/XMLSchema#string

Christopher M Evans

http://www.w3.org/2001/XMLSchema#string

Daniel N Harper

http://www.w3.org/2001/XMLSchema#string

David A Schwartz

http://www.w3.org/2001/XMLSchema#string

Dorota S Raclawska

http://www.w3.org/2001/XMLSchema#string

Elizabeth Sanchez

http://www.w3.org/2001/XMLSchema#string

Fani Ttofali

http://www.w3.org/2001/XMLSchema#string

Holger K Eltzschig

http://www.w3.org/2001/XMLSchema#string

Kristen N Kindrachuk

http://www.w3.org/2001/XMLSchema#string

P2860

Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis

SPDEF regulates goblet cell hyperplasia in the airway epithelium

IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production

IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.

Interleukin-13: central mediator of allergic asthma

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

Muc5b is required for airway defence

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

Airway mucus function and dysfunction.

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6281

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scholarly article

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10.1038/NCOMMS7281

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P478

6

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P50

Deborah R Liptzin

Michael R. Blackburn

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2015-02-17T00:00:00Z

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272511298

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25687754

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4333679

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