Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.
about
Identification of a new hormone-binding site on the surface of thyroid hormone receptorSelectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer.Recent advances in allosteric androgen receptor inhibitors for the potential treatment of castration-resistant prostate cancer.Constitutive activity of the androgen receptor.Detection of persistent organic pollutants binding modes with androgen receptor ligand binding domain by docking and molecular dynamics.In silico discovery and validation of potent small-molecule inhibitors targeting the activation function 2 site of human oestrogen receptor αOxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.Transcriptional Inhibitors Identified in a 160,000-Compound Small-Molecule DUX4 Viability Screen.Androgen receptor: structure, role in prostate cancer and drug discovery.Functional analysis of androgen receptor mutations that confer anti-androgen resistance identified in circulating cell-free DNA from prostate cancer patients.Silver(I)-Catalyzed Intramolecular Cyclizations of Epoxide-Propargylic Esters to 1,4-Oxazine Derivatives.Beyond the ligand-binding pocket: targeting alternate sites in nuclear receptors.Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer.Androgen receptor modulators: a marriage of chemistry and biology.The hurdle of antiandrogen drug resistance: drug design strategies.Recent Developments in Androgen Receptor Antagonists.Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation.Structures of androgen receptor bound with ligands: advancing understanding of biological functions and drug discovery.Identification and characterization of antibacterial compound(s) of cockroaches (Periplaneta americana).IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENINGDiethyl 4-meth-oxyoxalyl-3,5-diphenyl-pyrrolidine-2,2-dicarboxyl-ate.Combining silver- and organocatalysis: an enantioselective sequential catalytic approach towards pyrano-annulated pyrazoles.N-heterocyclic carbene-catalyzed highly enantioselective synthesis of substituted dihydropyranopyrazolones.Brønsted acid-catalyzed stereoselective [4+3] cycloadditions of ortho-hydroxybenzyl alcohols with N,N'-cyclic azomethine imines.Endocrine Disrupting Chemicals Mediated through Binding Androgen Receptor Are Associated with Diabetes Mellitus.Drug-Discovery Pipeline for Novel Inhibitors of the Androgen Receptor.Catalytic cascade aldol-cyclization of tertiary ketone enolates for enantioselective synthesis of keto-esters with a C-F quaternary stereogenic center.Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.Bypassing Drug Resistance Mechanisms of Prostate Cancer with Small Molecules that Target Androgen Receptor-Chromatin Interactions.
P2860
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P2860
Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Targeting the Binding Function ...... ptor through Virtual Screening
@nl
Targeting the binding function ...... tor through virtual screening.
@ast
Targeting the binding function ...... tor through virtual screening.
@en
type
label
Targeting the Binding Function ...... ptor through Virtual Screening
@nl
Targeting the binding function ...... tor through virtual screening.
@ast
Targeting the binding function ...... tor through virtual screening.
@en
prefLabel
Targeting the Binding Function ...... ptor through Virtual Screening
@nl
Targeting the binding function ...... tor through virtual screening.
@ast
Targeting the binding function ...... tor through virtual screening.
@en
P2093
P2860
P356
P1476
Targeting the binding function ...... ptor through virtual screening
@en
P2093
Artem Cherkasov
Clementine Feau
Emma Tomlinson Guns
Eric LeBlanc
Frank Q Han
Ka Hong Chan
Nathan A Lack
Paul S Rennie
Peter Axerio-Cilies
Peyman Tavassoli
P2860
P304
P356
10.1021/JM201098N
P407
P50
P577
2011-11-18T00:00:00Z