Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

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Determining the Balance Between Drug Efficacy and Safety by the Network and Biological System Profile of Its Therapeutic Target

P2860

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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Selective modulation of the an ...... pinal bulbar muscular atrophy.

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Selective modulation of the an ...... pinal bulbar muscular atrophy.

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type

Item

label

Selective modulation of the an ...... pinal bulbar muscular atrophy.

@en

Selective modulation of the an ...... pinal bulbar muscular atrophy.

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prefLabel

Selective modulation of the an ...... pinal bulbar muscular atrophy.

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Selective modulation of the an ...... pinal bulbar muscular atrophy.

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P1476

Selective modulation of the an ...... spinal bulbar muscular atrophy

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P2093

Albert R La Spada

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Anderson P Kanagaraj

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Ane Korff

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Baochang Fan

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Brett J Winborn

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Brian D Freibaum

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Bryce L Sopher

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Burgess B Freeman

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Emmanuelle R Quemin

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Helen C Miranda

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P2860

Differential inhibition of postnatal brain, spinal cord and body growth by a growth hormone antagonist

Modulation of Androgen Receptor Activation Function 2 by Testosterone and Dihydrotestosterone

A surface on the androgen receptor that allosterically regulates coactivator binding

Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening

Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening.

Targeting the binding function 3 (BF3) site of the androgen receptor through virtual screening. 2. development of 2-((2-phenoxyethyl) thio)-1H-benzimidazole derivatives

Fiji: an open-source platform for biological-image analysis.

Coregulator function: a key to understanding tissue specificity of selective receptor modulators

A small-molecule Nrf1 and Nrf2 activator mitigates polyglutamine toxicity in spinal and bulbar muscular atrophy

Native functions of the androgen receptor are essential to pathogenesis in a Drosophila model of spinobulbar muscular atrophy.

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nm.4500

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427-437

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scholarly article

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10.1038/NM.4500

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English

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Heather S Tillman

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2018-03-05T00:00:00Z

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29505030

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5975249

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Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

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P2860

P2860

Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

description

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P1433

P1476

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P356

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P356

P407

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