Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes
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The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceDeterminants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD InvestigationThe effect of environmental chemicals on the tumor microenvironmentCauses of genome instability: the effect of low dose chemical exposures in modern societyTargeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+)Distance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexesCobalt(III)porphyrin to target G-quadruplex DNA.Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behaviorAn omics perspective to the molecular mechanisms of anticancer metallo-drugs in the computational microscope era.Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor ActivityCrystallography of DNA and RNA G-quadruplex nucleic acids and their ligand complexes.Zinc complexes as fluorescent chemosensors for nucleic acids: new perspectives for a "boring" element.Metal complex interactions with DNA.Dinickel-Salphen Complexes as Binders of Human Telomeric Dimeric G-Quadruplexes.Interaction of oxovanadium(IV)-salphen complexes with bovine serum albumin and their cytotoxicity against cancer.Copper(II) complexes of substituted salicylaldehyde dibenzyl semicarbazones: synthesis, cytotoxicity and interaction with quadruplex DNA.Investigation of the interactions between Pt(II) and Pd(II) derivatives of 5,10,15,20-tetrakis (N-methyl-4-pyridyl) porphyrin and G-quadruplex DNA.The molecular mechanism of ligand unbinding from the human telomeric G-quadruplex by steered molecular dynamics and umbrella sampling simulations.Loop flexibility in human telomeric quadruplex small-molecule complexes.Another step toward DNA selective targeting: Ni(II) and Cu(II) complexes of a Schiff base ligand able to bind gene promoter G-quadruplexes.Intercalation processes of copper complexes in DNA.A conformationally flexible dinuclear Pt(II) complex with differential behavior of its two states toward quadruplex DNA.DNA interaction of CuII, NiII and ZnII functionalized salphen complexes: studies by linear dichroism, gel electrophoresis and PCR.A theoretical and experimental investigation of the spectroscopic properties of a DNA-intercalator salphen-type Zn(II) complex.Efficient Inhibition of Telomerase by Nickel-Salophen Complexes.Quadruplex DNA-Stabilising Dinuclear Platinum(II) Terpyridine Complexes with Flexible Linkers.A Redox-Activated G-Quadruplex DNA Binder Based on a Platinum(IV)-Salphen Complex.Novel Oligopyrrole Carboxamide based Nickel(II) and Palladium(II) Salens, Their Targeting of Human G-Quadruplex DNA, and Selective Cancer Cell Toxicity.Optical DNA Biosensor Based on Square-Planar Ethyl Piperidine Substituted Nickel(II) Salphen Complex for Dengue Virus Detection.Synthesis, Characterization and DNA-Binding Studies of Hydroxyl Functionalized Platinum(II) Salphen Complexes.Selective and Cooperative Ligand Binding to Antiparallel Human Telomeric DNA G-Quadruplexes.Enantioselective sulfoxidation reaction catalyzed by a G-quadruplex DNA metalloenzyme.Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.Development of microfluidic platforms for the synthesis of metal complexes and evaluation of their DNA affinity using online FRET melting assays.Structure and hydrodynamics of a DNA G-quadruplex with a cytosine bulge.Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD InvestigationLuminescent zinc salophen derivatives: cytotoxicity assessment and action mechanism studiesSolution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic bindingInteractions of Pt-ttpy with G-Quadruplexes Originating from Promoter Region of the c-myc Gene Deciphered by NMR and Gel Electrophoresis Analysis
P2860
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P2860
Molecular basis of structure-activity relationships between salphen metal complexes and human telomeric DNA quadruplexes
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@ast
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@en
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@nl
type
label
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@ast
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@en
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@nl
prefLabel
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@ast
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@en
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@nl
P2093
P356
P1476
Molecular basis of structure-a ...... man telomeric DNA quadruplexes
@en
P2093
Alan K Todd
Gary N Parkinson
Mekala Gunaratnam
Nancy H Campbell
Nurul H Abd Karim
Ramon Vilar
Vanessa Petrucci
P304
P356
10.1021/JM201140V
P407
P577
2012-01-12T00:00:00Z