Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily
about
Gene flow and biological conflict systems in the origin and evolution of eukaryotes.Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavageA New Method, "Reverse Yeast Two-Hybrid Array" (RYTHA), Identifies Mutants that Dissociate the Physical Interaction Between Elg1 and Slx5.Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancerTyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair.Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin.Tyrosyl-DNA phosphodiesterases: rescuing the genome from the risks of relaxation.Novel group of tyrosyl-DNA-phosphodiesterase 1 inhibitors based on disaccharide nucleosides as drug prototypes for anti-cancer therapy
P2860
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P2860
Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@ast
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@en
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@nl
type
label
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@ast
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@en
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@nl
prefLabel
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@ast
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@en
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@nl
P2093
P2860
P1476
Analysis of the Active-Site Me ...... he Phospholipase D Superfamily
@en
P2093
Donald Bashford
Evan Q Comeaux
Nagakumar Bharatham
Nauzanene Jafari
Robert C A M van Waardenburg
Stefan Gajewski
Stephen W White
P2860
P304
P356
10.1016/J.JMB.2011.11.044
P407
P577
2012-01-27T00:00:00Z