Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
about
Proteomic approaches and identification of novel therapeutic targets for alcoholismPathways and Barriers for Ion Translocation through the 5-HT3A Receptor ChannelCrystal structure of a human GABAA receptorGating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallographyInsights into Distinct Modulation of 7 and 7 2 Nicotinic Acetylcholine Receptors by the Volatile Anesthetic IsofluraneCrystal structures of a pentameric ligand-gated ion channel provide a mechanism for activationX-ray structure of the human α4β2 nicotinic receptorA Structural Model of the Human α7 Nicotinic Receptor in an Open ConformationEthanol effects on glycinergic transmission: From molecular pharmacology to behavior responsesX-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors.CHEXVIS: a tool for molecular channel extraction and visualizationIdentifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels.Identification of a pre-active conformation of a pentameric channel receptorA membrane-embedded pathway delivers general anesthetics to two interacting binding sites in the Gloeobacter violaceus ion channel.Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors.Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structureAllosteric regulation of pentameric ligand-gated ion channels: an emerging mechanistic perspectiveFunctional anatomy of an allosteric protein.The atypical cation-conduction and gating properties of ELIC underscore the marked functional versatility of the pentameric ligand-gated ion-channel fold.SCMMTP: identifying and characterizing membrane transport proteins using propensity scores of dipeptides.Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion ChannelA chimeric prokaryotic pentameric ligand-gated channel reveals distinct pathways of activation.Perturbation of Critical Prolines in Gloeobacter violaceus Ligand-gated Ion Channel (GLIC) Supports Conserved Gating Motions among Cys-loop Receptors.Role of the Fourth Transmembrane α Helix in the Allosteric Modulation of Pentameric Ligand-Gated Ion Channels.Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations.Intermediate closed state for glycine receptor function revealed by cysteine cross-linking.Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazineConduits of life's spark: a perspective on ion channel research since the birth of neuron.Engineering differential charge selectivity from a single structural template.A mechanism for acetylcholine receptor gating based on structure, coupling, phi, and flip.Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel.Pentameric Ligand-gated Ion Channels : Insights from Computation.Structure and Pharmacologic Modulation of Inhibitory Glycine Receptors.Detergents: Friends not foes for high-performance membrane proteomics toward precision medicine.Genuine open form of the pentameric ligand-gated ion channel GLIC.The M4 Transmembrane α-Helix Contributes Differently to Both the Maturation and Function of Two Prokaryotic Pentameric Ligand-gated Ion Channels.Function of the M1 π-helix in endplate receptor activation and desensitization.Probing residues in the pore-forming (M2) domain of the Cys-loop receptor homologue GLIC reveals some unusual features.Subcellular neuronal quasicrystals: Implications for consciousness.
P2860
Q27023085-E350C8D4-07F1-4310-A43F-C153009A8DC2Q27313796-FE0D4599-34AF-4B0D-BE33-5203C8CE7373Q27644591-8205894B-1C4B-4F04-973D-6C5942BD2ACEQ27680479-C3CF2E4A-B177-4271-ABC2-5657DC528F0EQ27680533-3B326C8E-631B-44BE-9542-E832776F5E23Q27681074-DA02E728-09FD-4CAC-B357-C2F8D878C967Q27728171-BBA800E8-3138-46CC-8224-52D021179B32Q28546747-0FC26278-EDD4-4B2F-BF5B-DBAB5292CAC3Q30371246-6A421746-6FAF-4C18-8A2D-164D5AA9DFCDQ30605151-B5836796-08EB-472C-BADF-C714420EB873Q30644529-5FED24C1-CA00-4D10-A782-88DBEA330805Q33364168-C726715A-F203-4E05-B74B-F6F72101B478Q33585840-72B3589F-353C-4E4B-B2AA-E673DE64BB21Q33781359-C9971C46-F986-420D-B849-954546905F17Q34518637-A635F0E9-A1A9-479F-81FB-E4F16676883CQ35156856-3EE5251D-324C-4CB0-89E4-AF4F5E6A3DB5Q35493550-822F5CAB-165B-4096-B2C9-F339BA52DAC9Q35531523-CF518203-AAB5-4865-8500-B5F28FBECEDBQ35795776-52405707-CADF-48CF-A689-A4E85AAB8081Q35871507-2FD9143D-0572-4389-A7C0-B4F418D988DDQ35933917-71755FA6-67F4-42B1-804A-933B10347151Q36102224-787FC062-1B61-4FA6-878C-F7CECF96A774Q36744700-BBDE31DC-6BEE-4048-852E-A40861625A35Q36777831-AC756F30-0977-4778-AF26-C60B1C3C5F67Q37237362-9C4E066C-6757-4929-86F5-EC7D9E342BF2Q37240430-4D6A1F09-B716-4742-B5A0-ECD1985E6C99Q37379919-D32CAF50-4D37-4726-8A8E-6C25FC72AC66Q37401733-A6395E54-CC5A-44F4-84A1-0C5F2B3F7C4AQ37417744-3ECA172E-C92C-4F00-A758-B208E20DB16BQ37565659-2858DFD1-DB95-485E-AA70-71BFB3A2388EQ37623366-E2B51F27-8195-4795-8D6F-65D2224BBE6CQ37735820-0B74AE2E-B742-4F2A-9241-EFD01CAF1C08Q38452843-9392A506-8060-479B-A815-056E665FE4D6Q38893053-6117C2CF-C9FA-41B4-BC53-51F92E25584CQ38955724-BE941F67-E663-4975-9F7B-9B26A7E0BA55Q39030477-FE8F6756-C548-43D9-9212-874D04C8DC00Q40595431-9C0A21CA-942D-42B0-BC0F-04AE766A3ECCQ40992011-A6F54B78-C92D-4E86-8BAA-17CC15E1D135Q41086129-1CBDF6CD-1B8F-4986-917F-E27D2C7D8261Q41278957-8A43B52B-DD2F-4FC2-8C71-172DE85F859C
P2860
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@ast
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@en
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@nl
type
label
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@ast
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@en
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@nl
prefLabel
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@ast
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@en
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
@en
P2093
Andrew W Thompson
Catherine Van Renterghem
Frédéric Poitevin
Gustavo Moraga-Cid
Laurie Malherbe
Ludovic Sauguet
Marc Baaden
Marc Delarue
Pierre-Jean Corringer
P2860
P304
P3181
P356
10.1038/EMBOJ.2013.17
P407
P577
2013-02-12T00:00:00Z