Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily
about
Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyondInsights into the prostanoid pathway in the ovary development of the penaeid shrimp Penaeus monodonCrystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISMCrystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving StrategyStructural basis for catalysis at the membrane-water interface.Systematic evaluation of CS-Rosetta for membrane protein structure prediction with sparse NOE restraints.Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol.Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme.A dynamic Asp-Arg interaction is essential for catalysis in microsomal prostaglandin E2 synthase.Characterization of microsomal prostaglandin E synthase 1 inhibitors.Dead-end complex, lipid interactions and catalytic mechanism of microsomal glutathione transferase 1, an electron crystallography and mutagenesis investigation.Arg126 and Asp49 Are Essential for the Catalytic Function of Microsomal Prostaglandin E2 Synthase 1 and Ser127 Is NotBreaking barriers to novel analgesic drug development.Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review.A Novel Multi-step Virtual Screening for the Identification of Human and Mouse mPGES-1 Inhibitors.Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.Accurate Prediction of Contact Numbers for Multi-Spanning Helical Membrane Proteins.Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.Prostaglandin terminal synthases as novel therapeutic targets.Recent advances in protein engineering and biotechnological applications of glutathione transferases.Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions.An Insect Prostaglandin E Synthase Acts in Immunity and Reproduction
P2860
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P2860
Crystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamily
description
2013 nî lūn-bûn
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2013 թուականի Մարտին հրատարակուած գիտական յօդուած
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2013 թվականի մարտին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
@zh-tw
2013年论文
@wuu
name
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@ast
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@en
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@nl
type
label
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@ast
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@en
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@nl
prefLabel
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@ast
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@en
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of microsoma ...... rsity in the MAPEG superfamily
@en
P2093
Johan Nord
Margareta Ek
Patrik Johansson
Stefan Geschwindner
Tove Sjögren
P2860
P304
P3181
P356
10.1073/PNAS.1218504110
P407
P577
2013-03-05T00:00:00Z