Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
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Eukaryotic translation elongation factor 1 gamma contains a glutathione transferase domain--study of a diverse, ancient protein superfamily using motif search and structural modelingThe crystal structures of glutathione S-transferases isozymes 1-3 and 1-4 from Anopheles dirus species BStructural contributions of delta class glutathione transferase active-site residues to catalysisCrystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamilyThe three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B regionCrystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stressThe three-dimensional structure of a class-Pi glutathione S-transferase complexed with glutathione: the active-site hydration provides insights into the reaction mechanismIdentification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesignRat glutathione S-transferase M4-4: an isoenzyme with unique structural features including a redox-reactive cysteine-115 residue that forms mixed disulphides with glutathioneThe glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistanceZebra: a web server for bioinformatic analysis of diverse protein families.Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in LigninMu-class glutathione transferase from Xenopus laevis: molecular cloning, expression and site-directed mutagenesisPolymorphism of the glutathione transferase subunit 3 in Sprague-Dawley rats involves a reactive cysteine residueForced evolution of glutathione S-transferase to create a more efficient drug detoxication enzyme.New structural and chemical insight into the catalytic mechanism of epoxide hydrolases.Glutathione transferases: a structural perspective.Prediction of substrates for glutathione transferases by covalent docking.Macromolecular Crystallography and Structural Biology Databases at NIST.Three-dimensional structure of Schistosoma japonicum glutathione S-transferase fused with a six-amino acid conserved neutralizing epitope of gp41 from HIVSelf-consistently optimized statistical mechanical energy functions for sequence structure alignment.Probing the active site of alpha-class rat liver glutathione S-transferases using affinity labeling by monobromobimane.Amino acid sequencing, molecular cloning and modelling of the chick liver class-theta glutathione S-transferase CL1.Characterization of the binding of 8-anilinonaphthalene sulfonate to rat class Mu GST M1-1.Structure-Based Design of Anticancer Prodrug PABA/NO.Crystal structure of a theta-class glutathione transferase.Mechanisms of induction of cytosolic and microsomal glutathione transferase (GST) genes by xenobiotics and pro-inflammatory agents.Nitrosylation of human glutathione transferase P1-1 with dinitrosyl diglutathionyl iron complex in vitro and in vivo.Determination of Rab5 activity in the cell by effector pull-down assay.Modeling the active sites of cytochrome P450s and glutathione S-transferases, two of the most important biotransformation enzymes.Steady-state kinetics and chemical mechanism of octopus hepatopancreatic glutathione transferase.Modification of glutathione S-transferase 3-3 mutants with 2-(S-glutathionyl)-3,5,6-trichloro-1,4-benzoquinone. Identification of the C-terminal tryptic fragment as part of the H-site and evidence that 2-(S-glutathionyl)-3,5,6-trichloro-1,4-benzoquiAmino acid sequence of glutathione S-transferase rGSTM5* from rat testis.Mass spectrometric analysis of rat liver cytosolic glutathione S-transferases: modifications are limited to N-terminal processing.Binding of the aflatoxin-glutathione conjugate to mouse glutathione S-transferase A3-3 is saturated at only one ligand per dimer.A group of sequence-related sphingomonad enzymes catalyzes cleavage of β-aryl ether linkages in lignin β-guaiacyl and β-syringyl ether dimers.Contribution of the mu loop to the structure and function of rat glutathione transferase M1-1.Human glutathione transferase A1-1 demonstrates both half-of-the-sites and all-of-the-sites reactivity.Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.Ligand-based protein alignment and isozyme specificity of glutathione S-transferase inhibitors.
P2860
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P2860
Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene
description
1994 nî lūn-bûn
@nan
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@ast
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@en
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@nl
type
label
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@ast
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@en
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
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prefLabel
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
@ast
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
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Structure and function of the ...... droxy-9,10-dihydrophenanthrene
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P2093
P356
P1433
P1476
Structure and function of the ...... droxy-9,10-dihydrophenanthrene
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P2093
G L Gilliland
R N Armstrong
S M Prasad
W W Johnson
P304
P356
10.1021/BI00171A002
P407
P50
P577
1994-02-01T00:00:00Z