Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors

Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors

Item
http://www.wikidata.org/entity/Q27677423
The ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!Discovery of Novel Trypanosoma brucei Phosphodiesterase B1 Inhibitors by Virtual Screening against the Unliganded TbrPDEB1 Crystal StructureThe Potential of Secondary Metabolites from Plants as Drugs or Leads against Protozoan Neglected Diseases-Part III: In-Silico Molecular Docking InvestigationsAntiprotozoal Activity Profiling of Approved Drugs: A Starting Point toward Drug RepositioningNew compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.Down regulation of NO signaling in Trypanosoma cruzi upon parasite-extracellular matrix interaction: changes in protein modification by nitrosylation and nitrationStructural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric InhibitorCharacterization of parasite-specific indels and their proposed relevance for selective anthelminthic drug targeting.cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target.The single cyclic nucleotide-specific phosphodiesterase of the intestinal parasite Giardia lamblia represents a potential drug target.A Unique Sub-Pocket for Improvement of Selectivity of Phosphodiesterase Inhibitors in CNS.Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.Rational Selection of Anti-Microbial Drug Targets: Unique or Conserved?
P2860

Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors

Item
http://www.wikidata.org/entity/Q27677423
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
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2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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type
label
Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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prefLabel
Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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Biological and Structural Char ...... Parasite Selective Inhibitors
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P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932