Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases
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Structural analysis of the KANSL1/WDR5/KANSL2 complex reveals that WDR5 is required for efficient assembly and chromatin targeting of the NSL complexHijacked in cancer: the KMT2 (MLL) family of methyltransferasesOn WD40 proteins: propelling our knowledge of transcriptional control?Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complexStructural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1Molecular basis for DPY-30 association to COMPASS-like and NURF complexesTargeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesA non-active-site SET domain surface crucial for the interaction of MLL1 and the RbBP5/Ash2L heterodimer within MLL family core complexesA phosphorylation switch on RbBP5 regulates histone H3 Lys4 methylation.Biochemical reconstitution and phylogenetic comparison of human SET1 family core complexes involved in histone methylationWD repeat-containing protein 5 (WDR5) localizes to the midbody and regulates abscission.Epigenetics: Disrupting histone lysine methylation.Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase ComplexAutomethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.Inhibitors of Protein Methyltransferases and Demethylases.Targeting human SET1/MLL family of proteins.A SET-domain-independent role of WRAD complex in cell-cycle regulatory function of mixed lineage leukemia.Diverse roles of WDR5-RbBP5-ASH2L-DPY30 (WRAD) complex in the functions of the SET1 histone methyltransferase family.Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells.H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass.Identification of putative SNPs in progressive retinal atrophy affected Canis lupus familiaris using exome sequencing.Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.Resolving Affinity Purified Protein Complexes by Blue Native PAGE and Protein Correlation Profiling.Structural basis of arginine asymmetrical dimethylation by PRMT6.Assembling a COMPASS.Conference scene: 2nd cancer epigenetics conference.Moonlighting with WDR5: A Cellular Multitasker.The COMPASS-like complex promotes flowering and panicle branching in rice.WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.Facile target validation in an animal model with intracellularly expressed monobodies
P2860
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P2860
Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases
description
2012 nî lūn-bûn
@nan
2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@ast
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@en
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@nl
type
label
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@ast
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@en
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@nl
prefLabel
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@ast
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@en
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@nl
P2093
P2860
P356
P1476
Structural Basis for WDR5 Inte ...... ily Histone Methyltransferases
@en
P2093
Anamika Patel
David G Skalnik
Jeong-Heon Lee
Michael S Cosgrove
Venkatasubramanian Dharmarajan
P2860
P304
P356
10.1074/JBC.M112.364125
P407
P577
2012-08-10T00:00:00Z