SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
about
How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair PathwaySlx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.Mgm101: A double-duty Rad52-like protein.Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands.Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres.Conditional genetic interactions of RTT107, SLX4, and HRQ1 reveal dynamic networks upon DNA damage in S. cerevisiae.Telomerase enzymatic component hTERT shortens long telomeres in human cells.The basic N-terminal domain of TRF2 limits recombination endonuclease action at human telomeresIncreased meiotic crossovers and reduced genome stability in absence of Schizosaccharomyces pombe Rad16 (XPF).Noncovalent interactions with SUMO and ubiquitin orchestrate distinct functions of the SLX4 complex in genome maintenance.Defective repair of uracil causes telomere defects in mouse hematopoietic cells.SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites.The ERCC1 and ERCC4 (XPF) genes and gene productsSLX4 contributes to telomere preservation and regulated processing of telomeric joint molecule intermediatesAn H2A Histone Isotype, H2ac, Associates with Telomere and Maintains Telomere Integrity.NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres.Complex interactions between the DNA-damage response and mammalian telomeres.UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.A higher-order entity formed by the flexible assembly of RAP1 with TRF2.TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions.Dimerization of SLX4 contributes to functioning of the SLX4-nuclease complex.Fanconi anemia proteins in telomere maintenance.TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End ProtectionQuality control of homologous recombination.Nuclease delivery: versatile functions of SLX4/FANCP in genome maintenance.Arsenic-induced sumoylation of Mus81 is involved in regulating genomic stability.Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging.Convergence of The Nobel Fields of Telomere Biology and DNA Repair.DNA Replication Origins and Fork Progression at Mammalian TelomeresCrystal structure and SUMO binding of Slx1-Slx4 complex.Expression of Telomere-Associated Proteins is Interdependent to Stabilize Native Telomere Structure and Telomere Dysfunction by G-Quadruplex Ligand Causes TERRA Upregulation.Telomeric TERB1-TRF1 interaction is crucial for male meiosis.BLM and SLX4 play opposing roles in recombination-dependent replication at human telomeres.The Structure-Specific Endonucleases MUS81 and SEND1 Are Essential for Telomere Stability in Arabidopsis.The Detection and Analysis of Chromosome Fragile Sites.The C-terminal extension unique to the long isoform of the shelterin component TIN2 enhances its interaction with TRF2 in a phosphorylation- and dyskeratosis congenita-cluster-dependent fashion.
P2860
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
P248
Q26752451-F3D08A80-251C-452D-98D0-586A7FD31825Q27934090-6CA5B75B-5C0A-4405-BC0B-474A8444D0D5Q30393025-60BD7ADC-9628-494A-BE54-007270C8D67CQ33558285-72B92264-4EB8-4B3A-9CF8-7AC32F4FAF29Q33605965-DB92F4A7-D455-4559-B714-E1A7749B9071Q33784933-1D697AC7-2593-4B13-A235-8CA42F61B2CEQ33952974-C59C6B99-B945-44C7-A3BE-5361DF1E3D3CQ34028576-712C080F-DF1C-483C-8826-328A9AE9CE95Q34636209-735D79F8-9A69-416B-B3CC-ED22007E86E9Q34898909-3622B47B-4B0B-4A40-A91B-76E466E79D0AQ35126631-5F8579D7-DD64-4248-93D7-8FBCDAA94BC4Q35568644-997C9F50-C564-4D70-AA60-AB9C64A33884Q35663361-EB0CD39A-9536-4094-86F6-BA0EA74A8914Q35842523-0DE36726-2840-493F-AEB2-FE270DDADDAAQ36030762-A3E5AC0A-74BC-41E9-8E12-9D5432048030Q36285037-48FE1C0E-8705-4628-9540-FA47CCCA09C9Q36539673-09B3A200-BC73-41EB-8DA4-88F768FAEE5AQ36566344-9195927D-842B-438A-9914-133560A5736AQ36627966-44B189B4-ED8F-4A59-9C62-0F6FE0EBD581Q36670262-8E9B3E19-C2DF-4DA1-AD17-6F0C1679AB08Q36959122-C4038995-883D-46DC-BDE5-31996F905051Q37029661-6B4E72E5-94EB-4D8E-A5C4-B7C035F6D1E9Q37210618-989E3181-8699-4639-B845-351A8CE61342Q38214443-8E7F0E43-CAE4-4AB3-AEBD-AAA17F6877AFQ38220992-EC5428EF-636C-41EB-857E-7DA225A5E70CQ38711574-3E7A74C5-EDDA-4F98-A17A-C1160B08EA71Q38844069-50E0CA30-FAE6-4D41-9999-73262339D701Q39012874-869A5F21-9A02-426F-9B4C-128792001AEBQ39204805-321E9997-665B-4461-AF98-F33DF7565B20Q43069093-20165BB1-2A95-422B-89CB-402F4F220873Q47406137-3603569A-4ED0-425B-9198-4DDAF121A1C8Q47588655-8F732942-53E2-42CC-BAB3-3FFEA79F989DQ47846631-485ED6FE-2CE3-48EE-A4EB-9C0E182DA6A0Q48274589-49F64910-707D-4EA6-BCB4-AD528B743758Q50086359-A74E65C8-E38C-47A8-9B2E-825B0214B7D5Q52341133-4382CB13-425C-47CA-B152-7B8E69439F35
P2860
SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
description
2013 nî lūn-bûn
@nan
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@ast
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@en
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@nl
type
label
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@ast
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@en
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@nl
prefLabel
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@ast
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@en
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@nl
P2093
P2860
P921
P3181
P1433
P1476
SLX4 Assembles a Telomere Main ...... e Endonucleases with Telomeres
@en
P2093
Eun Young Yu
Jaya Sarkar
Kent Horvath
Neal F Lue
P2860
P3181
P356
10.1016/J.CELREP.2013.08.017
P577
2013-09-12T00:00:00Z