Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
about
Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substratesProliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesisThe human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structuresA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityA genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stabilityDNA repair. Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-linksHuman GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctionsIdentification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repairA small-cell lung cancer genome with complex signatures of tobacco exposureMutations of the SLX4 gene in Fanconi anemiaMolecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systemsDisruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemiaCooperativity of the SUMO and Ubiquitin Pathways in Genome StabilityInhibition of Topoisomerase (DNA) I (TOP1): DNA Damage Repair and Anticancer TherapyHold your horSSEs: controlling structure-selective endonucleases MUS81 and Yen1/GEN1Nucleases in homologous recombination as targets for cancer therapyThe Fanconi anemia pathway and DNA interstrand cross-link repairTelomeres-structure, function, and regulationRescuing stalled or damaged replication forksMechanism and regulation of incisions during DNA interstrand cross-link repairDiseases associated with defective responses to DNA damageDNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapyNucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signalsCombinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleasesMammalian BTBD12 (SLX4) protects against genomic instability during mammalian spermatogenesisCaenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediatesStructures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin LigasesA dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repairA winged helix domain in human MUS81 binds DNA and modulates the endonuclease activity of MUS81 complexesSLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with TelomeresHow SLX4 cuts through the mystery of HIV-1 Vpr-mediated cell cycle arrest.The DNA Damage Response: Making It Safe to Play with KnivesGenetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast.Role of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeastRecovery from the DNA Replication CheckpointSnaps and mends: DNA breaks and chromosomal translocationsThe endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivoUSP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responsesXPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4
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P2860
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@ast
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en-gb
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@nl
type
label
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@ast
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en-gb
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@nl
prefLabel
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@ast
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en-gb
Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@nl
P2093
P2860
P50
P921
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Mammalian BTBD12/SLX4 assemble ...... and is required for DNA repair
@en
P2093
Brenda C O'Connell
J Wade Harper
Jennifer M Svendsen
Mathew E Sowa
P2860
P3181
P356
10.1016/J.CELL.2009.06.030
P407
P577
2009-07-10T00:00:00Z