Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
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The endosomal-lysosomal system: from acidification and cargo sorting to neurodegenerationNew insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysinSuppression of asparaginyl endopeptidase attenuates breast cancer-induced bone pain through inhibition of neurotrophin receptors.Trichomonas vaginalis Cysteine Proteinases: Iron Response in Gene Expression and Proteolytic Activity.Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's diseaseN4 DNA recognition by STAT6: structural and functional implications.Proteolysis mediated by cysteine cathepsins and legumain-recent advances and cell biological challenges.Macrocyclization by asparaginyl endopeptidases.Endolysin LysEF-P10 shows potential as an alternative treatment strategy for multidrug-resistant Enterococcus faecalis infections.Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart.Distinct Roles of Catalytic Cysteine and Histidine in the Protease and Ligase Mechanisms of Human Legumain As Revealed by DFT-Based QM/MM Simulations.Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain.Structural basis of ribosomal peptide macrocyclization in plants.Overexpression of asparaginyl endopeptidase is significant for esophageal carcinoma metastasis and predicts poor patient prognosis.Crystal structure of plant legumain reveals a unique two-chain state with pH-dependent activity regulation.Structural analyses of Arabidopsis thaliana legumain γ reveal the differential recognition and processing of proteolysis and ligation substrates.BDNF inhibits neurodegenerative disease-associated asparaginyl endopeptidase activity via phosphorylation by AKT
P2860
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P2860
Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structural analysis of asparag ...... intermediate maturation stage
@ast
Structural analysis of asparag ...... intermediate maturation stage
@en
Structural analysis of asparag ...... intermediate maturation stage
@nl
type
label
Structural analysis of asparag ...... intermediate maturation stage
@ast
Structural analysis of asparag ...... intermediate maturation stage
@en
Structural analysis of asparag ...... intermediate maturation stage
@nl
prefLabel
Structural analysis of asparag ...... intermediate maturation stage
@ast
Structural analysis of asparag ...... intermediate maturation stage
@en
Structural analysis of asparag ...... intermediate maturation stage
@nl
P2093
P2860
P356
P1433
P1476
Structural analysis of asparag ...... intermediate maturation stage
@en
P2093
Christopher Crowley
Genhong Cheng
Keqiang Ye
Lianying Jiao
Lixia Zhao
Songying Ouyang
P2860
P2888
P304
P356
10.1038/CR.2014.4
P577
2014-03-01T00:00:00Z
P6179
1021987508