Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.
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Harnessing the protective potential of HIV-1 neutralizing antibodiesCurrent Advances in Virus-Like Particles as a Vaccination Approach against HIV InfectionThe HIV glycan shield as a target for broadly neutralizing antibodiesRecent strategies targeting HIV glycans in vaccine designDesigning synthetic vaccines for HIVAntibody responses to envelope glycoproteins in HIV-1 infectionVirological features associated with the development of broadly neutralizing antibodies to HIV-1HIV broadly neutralizing antibody targetsVaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding SiteDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityAntiviral Therapy by HIV-1 Broadly Neutralizing and Inhibitory AntibodiesAntibody potency relates to the ability to recognize the closed, pre-fusion form of HIV EnvStructural Constraints Determine the Glycosylation of HIV-1 Envelope TrimersCell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 EnvelopeGlycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodiesImmunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing EpitopesAn efficiently cleaved HIV-1 clade C Env selectively binds to neutralizing antibodiesMost neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunitsHIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimersComposition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope GlycoproteinComputational tools for epitope vaccine design and evaluationA novel neutralizing monoclonal antibody targeting the N-terminal domain of the MERS-CoV spike proteinA Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesAntigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV InfectionFlow virometry analysis of envelope glycoprotein conformations on individual HIV virions.HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence.Challenges in HIV Vaccine Research for Treatment and Prevention.A novel, live-attenuated vesicular stomatitis virus vector displaying conformationally intact, functional HIV-1 envelope trimers that elicits potent cellular and humoral responses in mice.Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41.Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity.Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success.Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity.Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies.Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.Drift of the HIV-1 envelope glycoprotein gp120 toward increased neutralization resistance over the course of the epidemic: a comprehensive study using the most potent and broadly neutralizing monoclonal antibodies.
P2860
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P2860
Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.
description
2014 nî lūn-bûn
@nan
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structural Delineation of a Qu ...... ce on Intact HIV-1 Env Trimers
@nl
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@ast
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@en
type
label
Structural Delineation of a Qu ...... ce on Intact HIV-1 Env Trimers
@nl
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@ast
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@en
prefLabel
Structural Delineation of a Qu ...... ce on Intact HIV-1 Env Trimers
@nl
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@ast
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@en
P2093
P2860
P50
P3181
P1433
P1476
Structural delineation of a qu ...... e on intact HIV-1 Env trimers.
@en
P2093
Alba Torrents de la Peña
Albert Cupo
Andrew B Ward
Claudia Blattner
Dennis R Burton
Emilia Falkowska
James C Paulson
John P Moore
Kwinten Sliepen
Marit van Gils
P2860
P304
P3181
P356
10.1016/J.IMMUNI.2014.04.008
P407
P577
2014-04-24T00:00:00Z