Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
about
Harnessing the protective potential of HIV-1 neutralizing antibodiesDynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane FusionThe HIV glycan shield as a target for broadly neutralizing antibodiesDesigning synthetic vaccines for HIVAntibody responses to envelope glycoproteins in HIV-1 infectionVirological features associated with the development of broadly neutralizing antibodies to HIV-1HIV broadly neutralizing antibody targetsSynaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationMucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIVmac251 Rectal ChallengeVaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding SiteCrystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 EnvStructures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine designOptimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based DesignDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityAntiviral Therapy by HIV-1 Broadly Neutralizing and Inhibitory AntibodiesReverse vaccinology 2.0: Human immunology instructs vaccine antigen designTargeting host-derived glycans on enveloped viruses for antibody-based vaccine designStructural Constraints Determine the Glycosylation of HIV-1 Envelope TrimersGlycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodiesImmunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing EpitopesHIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimersComposition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope GlycoproteinRecent Insights into the HIV/AIDS Pandemic.HIV-1 Glycan Density Drives the Persistence of the Mannose Patch within an Infected Individual.Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals.Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV InfectionGlycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope GlycoproteinHIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Antibody 10-1074 suppresses viremia in HIV-1-infected individualsInsights into vaccine development for acquired immune deficiency syndrome from crystal structures of human immunodeficiency virus-1 gp41 and equine infectious anemia virus gp45.Inhibition of HIV Entry by Targeting the Envelope Transmembrane Subunit gp41.Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.Neutralizing Monoclonal Antibodies to Fight HIV-1: On the Threshold of Success.Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication.Conformational dynamics of single HIV-1 envelope trimers on the surface of native virionsImproving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes.A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene.Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannoseComprehensive antigenic map of a cleaved soluble HIV-1 envelope trimer.
P2860
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P2860
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@ast
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@en
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@nl
type
label
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@ast
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@en
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@nl
prefLabel
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@ast
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@en
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@nl
P2093
P2860
P50
P356
P1433
P1476
Broad and potent HIV-1 neutral ...... inds the gp41-gp120 interface.
@en
P2093
Alba Torrents de la Peña
Aliaksandr Druz
Andrew B Ward
Byong H Kang
Gwo-Yu Chuang
Hiromi Imamichi
Ivelin S Georgiev
James M Binley
Jinghe Huang
Kwinten Sliepen
P2860
P2888
P304
P356
10.1038/NATURE13601
P407
P577
2014-09-03T00:00:00Z