Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells
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Structural Studies on Dinuclear Ruthenium(II) Complexes That Bind Diastereoselectively to an Antiparallel Folded Human Telomere SequenceDeterminants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD InvestigationNMR Structure of a Triangulenium-Based Long-Lived Fluorescence Probe Bound to a G-QuadruplexDistance measurements between paramagnetic ligands bound to parallel stranded guanine quadruplexesSpecific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.Exploring the Dynamics of Propeller Loops in Human Telomeric DNA Quadruplexes Using Atomistic Simulations.G-quadruplex structures and their interaction diversity with ligands.Indolo[3,2-c]quinoline G-quadruplex stabilizers: a structural analysis of binding to the human telomeric G-quadruplex.A Personal History of Quadruplex-Small Molecule Targeting.A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancerSynthesis, Binding and Antiviral Properties of Potent Core-Extended Naphthalene Diimides Targeting the HIV-1 Long Terminal Repeat Promoter G-QuadruplexesDiscovery of new G-quadruplex binding chemotypes.G-quadruplex structures in the human genome as novel therapeutic targets.Conformation-sensitive nucleoside analogues as topology-specific fluorescence turn-on probes for DNA and RNA G-quadruplexes.The unfolded protein response and cellular senescence. A review in the theme: cellular mechanisms of endoplasmic reticulum stress signaling in health and disease.Mapping and characterization of G-quadruplexes in Mycobacterium tuberculosis gene promoter regions.The molecular mechanism of ligand unbinding from the human telomeric G-quadruplex by steered molecular dynamics and umbrella sampling simulations.Divalent Naphthalene Diimide Ligands Display High Selectivity for the Human Telomeric G-quadruplex in K+ Buffer.Loop flexibility in human telomeric quadruplex small-molecule complexes.A red-NIR fluorescent dye detecting nuclear DNA G-quadruplexes: in vitro analysis and cell imaging.Hydrosoluble and solvatochromic naphthalene diimides with NIR absorption.Synthesis, Binding Properties, and Differences in Cell Uptake of G-Quadruplex Ligands Based on Carbohydrate Naphthalene Diimide Conjugates.Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule.A naphthalene diimide dyad for fluorescence switch-on detection of G-quadruplexes.A bimodal fluorescent and photocytotoxic naphthalene diimide for theranostic applications.G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy.Delineation of G-Quadruplex Alkylation Sites Mediated by 3,6-Bis(1-methyl-4-vinylpyridinium iodide)carbazole-Aniline Mustard Conjugates.Extended Naphthalene Diimides with Donor/Acceptor Hydrogen-Bonding Properties Targeting G-Quadruplex Nucleic AcidsChemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplexA Catalytic and Selective Scissoring Molecular Tool for Quadruplex Nucleic AcidsDeterminants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation
P2860
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P2860
Structure-based design and evaluation of naphthalene diimide G-quadruplex ligands as telomere targeting agents in pancreatic cancer cells
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2013 nî lūn-bûn
@nan
2013 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի ապրիլին հրատարակված գիտական հոդված
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年學術文章
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name
Structure-based design and eva ...... nts in pancreatic cancer cells
@ast
Structure-based design and eva ...... nts in pancreatic cancer cells
@en
Structure-based design and eva ...... nts in pancreatic cancer cells
@nl
type
label
Structure-based design and eva ...... nts in pancreatic cancer cells
@ast
Structure-based design and eva ...... nts in pancreatic cancer cells
@en
Structure-based design and eva ...... nts in pancreatic cancer cells
@nl
prefLabel
Structure-based design and eva ...... nts in pancreatic cancer cells
@ast
Structure-based design and eva ...... nts in pancreatic cancer cells
@en
Structure-based design and eva ...... nts in pancreatic cancer cells
@nl
P2093
P356
P1476
Structure-based design and eva ...... nts in pancreatic cancer cells
@en
P2093
Aaron G Dale
Anthony P Reszka
Gavin W Collie
Ingrida Pazitna
Marialuisa Micco
Mekala Gunaratnam
Stephan A Ohnmacht
P304
P356
10.1021/JM301899Y
P407
P577
2013-04-11T00:00:00Z