A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties
about
The Fe-S cluster-containing NEET proteins mitoNEET and NAF-1 as chemotherapeutic targets in breast cancer.Interactions between mitoNEET and NAF-1 in cells.Breast cancer tumorigenicity is dependent on high expression levels of NAF-1 and the lability of its Fe-S clustersPhylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates.Cancer-Related NEET Proteins Transfer 2Fe-2S Clusters to Anamorsin, a Protein Required for Cytosolic Iron-Sulfur Cluster Biogenesis.Molecular Dynamics Simulations of the [2Fe-2S] Cluster-Binding Domain of NEET Proteins Reveal Key Molecular Determinants That Induce Their Cluster Transfer/Release.Structure of the human monomeric NEET protein MiNT and its role in regulating iron and reactive oxygen species in cancer cells.The unique fold and lability of the [2Fe-2S] clusters of NEET proteins mediate their key functions in health and disease.Phylogenetic analysis of the CDGSH iron-sulfur binding domain reveals its ancient origin.
P2860
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P2860
A point mutation in the [2Fe–2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties
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2014 nî lūn-bûn
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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2014 թվականի հունիսին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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A point mutation in the [2Fe–2 ...... s the cluster donor properties
@ast
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@en
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@nl
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label
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@ast
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@en
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@nl
prefLabel
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@ast
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@en
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@nl
P2093
P2860
P1476
A point mutation in the [2Fe–2 ...... s the cluster donor properties
@en
P2093
Andrea R Conlan
Colin H Lipper
Jason T Stofleth
Mark L Paddock
Oded Livnah
Patricia A Jennings
Ron Mittler
Sagi Tamir
Yael Eisenberg-Domovich
P2860
P304
P356
10.1107/S1399004714005458
P577
2014-06-01T00:00:00Z