Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine - Wikidata - wikimedia - TriplyDB

Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine

Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine

http://www.wikidata.org/entity/Q27684466

about

N7 methylation alters hydrogen-bonding patterns of guanine in duplex DNA Substrate-induced DNA polymerase β activation.Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.Visualizing transient Watson-Crick-like mispairs in DNA and RNA duplexes.Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication.Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase β.Molecular analysis of the dual targeting of the epidermal growth factor receptor and the O-methylguanine-DNA methyltransferase with a double arm hybrid molecule Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Replication

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P2860

Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine

http://www.wikidata.org/entity/Q27684466

description

2014 nî lūn-bûn

@nan

2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հուլիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Transition-state destabilizati ...... stable lesion N7-methylguanine

@ast

Transition-state destabilizati ...... stable lesion N7-methylguanine

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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type

label

Transition-state destabilizati ...... stable lesion N7-methylguanine

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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prefLabel

Transition-state destabilizati ...... stable lesion N7-methylguanine

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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Nucleic Acids Research

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Transition-state destabilizati ...... stable lesion N7-methylguanine

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Hala Ouzon-Shubeita

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Myong-Chul Koag

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Seongmin Lee

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P2860

Instability and decay of the primary structure of DNA

Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin

Structures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during Misincorporation

Synthesis and Structure of Duplex DNA Containing the Genotoxic Nucleobase Lesion N7-Methylguanine

Replication infidelity via a mismatch with Watson–Crick geometry

Bypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IV

Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

DNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA Polymerase

Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η.

Amino Acid Substitution in the Active Site of DNA Polymerase β Explains the Energy Barrier of the Nucleotidyl Transfer Reaction

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scholarly article

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10.1093/NAR/GKU554

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13

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