Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G - Wikidata - wikimedia - TriplyDB

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

http://www.wikidata.org/entity/Q27684773

about

Signalling to eIF4E in cancer Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation eIF4F: a retrospective The cap-binding site of influenza virus protein PB2 as a drug target.Protein-protein interactions as drug targets.Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1 The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex 1H, 13C, and 15N backbone chemical shift assignments of 4E-BP144-87 and 4E-BP144-87 bound to eIF4E.Heat shock protein-27 (HSP27) regulates STAT3 and eIF4G levels in first trimester human placenta.Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation.The molecular choreography of protein synthesis: translational control, regulation, and pathways.Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics.Targeting of protein translation as a new treatment paradigm for prostate cancer.Eukaryotic translation initiation factors and cancer.The eukaryotic translation initiation factor eIF4E wears a "cap" for many occasions.Analysis of the interacting partners eIF4F and 3'-CITE required for Melon necrotic spot virus cap-independent translation.High-Throughput Chemical Probing of Full-Length Protein-Protein Interactions.Induction of the p53 Tumor Suppressor in Cancer Cells through Inhibition of Cap-Dependent Translation.The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex eIF4E-Dependent Translational Control: A Central Mechanism for Regulation of Pain Plasticity

P2860

Q26777735-549B6362-BAA3-459D-A18A-BD3ADFE6D813 Q27727984-2E68B308-50FF-41EF-8790-1D91AF408D80 Q28266825-7E51A6D8-0AEE-4F15-BC13-0A7408D35BDB Q30384645-2734B7CC-7017-49DB-8B74-988754781B39 Q35824701-588E1DBB-12CA-47DB-9A09-EA29ED3C1948 Q35909996-058ACA15-2CD6-4EA8-9975-CFC5B153A198 Q37255081-66B65115-9536-4991-950E-C951A502B31C Q38739339-48EF4156-640A-4553-BF15-A96576C9FC52 Q38742121-8D9F2BCA-7ACC-4252-9E3C-701CD42D771B Q38776106-FB30D4D6-24C9-4F66-BF1C-31E896615C74 Q38961838-149BFDB8-8595-42BE-B2E3-804F199D6F11 Q39068205-49130E9D-716B-4A5A-80CD-5D857D7C04AE Q39172901-664B82E9-0B08-48B2-B9D0-96091EDE17CF Q39400409-ED6832B0-2C21-472D-BBCE-558E25F969BD Q39549442-9EF13CEC-AA46-4E5C-8D7B-736BBE3FBAA7 Q39795195-B12E5710-0767-4639-BDA4-46BDFB53B8AD Q47431069-8446BB77-C92D-4663-875A-1CD6FDAE8162 Q52684406-B36D5FB4-7CA1-44C0-9409-C49BF0796239 Q58217735-2DE878DC-A0B8-4F95-B3F2-9CA48AC33609 Q59136306-562180DA-E3BB-4FB5-ACF9-29E1FC53662F

P2860

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G

http://www.wikidata.org/entity/Q27684773

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@ast

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@en

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@nl

type

label

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@ast

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@en

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@nl

prefLabel

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@ast

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@en

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@nl

P1433

Q27684773-1ADB40E7-C317-4D72-94E5-77D4388DE886

P1476

Q27684773-FE6D8CDB-8501-402E-A098-A7A7D8873173

P2093

Q27684773-2535FFF0-EFDB-4F3F-BBC4-DAF847DA6BE4

Q27684773-5D4D0596-68AC-4445-ACA4-5213E491AFE7

Q27684773-5F4B643C-50E3-4A21-B6CF-31689A11F74D

Q27684773-76B67340-2E39-4615-9231-58C60719AC76

Q27684773-89E5FE48-C43E-4CB2-8A14-545C1EBEB1D9

Q27684773-A4634476-7328-4971-99DC-69128F42A626

Q27684773-A70B4A5F-DC3C-4C0B-9634-1D7D80894B45

Q27684773-C90CCA64-3B3C-4366-B0F9-0271221215F0

Q27684773-CD6481AF-48FB-4CD9-8339-87DB70D82D27

Q27684773-D775A48C-54EF-4267-A807-B2BB6457C19B

P2860

Q27684773-0671D9DC-1CEC-4712-9193-5D0A60319F71

Q27684773-088906E2-166F-425B-B70B-889C28E07528

Q27684773-0CF47CC9-5329-4406-95FC-D09A3B78D859

Q27684773-177E2173-7C27-485B-BE55-332B2FE875ED

Q27684773-26531765-B820-41BC-8E6F-1BD53A1E9320

Q27684773-27A52823-934E-405B-A2B4-1638A0C0D585

Q27684773-295CEFE1-15EF-4454-BC4C-C14091D4E1CF

Q27684773-3198D223-5063-460B-A2AC-36D4B7C6D148

Q27684773-3465D0DA-032E-4CDD-96F5-E18B2E6901C9

Q27684773-3520AC30-04AB-4B2B-83DF-19C2CCCE0872

P304

Q27684773-7D04453B-8513-4DA2-AD0F-8234C84C2485

P31

Q27684773-35F081DA-0DB9-41EE-8D33-0B4CB996D2D4

P3181

Q27684773-24337580-6B9E-4236-8BA9-1E95835D1B93

P356

Q27684773-67FE6C58-293F-4907-8B8C-7003B32FE2CB

P407

Q27684773-8B1D58AA-C11C-4812-826A-4BE83BF39132

P433

Q27684773-41472386-FA18-4354-8A81-AF617E60636E

P478

Q27684773-8B7DCAA2-25D7-4944-BDCB-4C0BDBAD28F1

P50

Q27684773-5BBAA43C-8DF8-4869-9BA4-4CD92D70B1BE

Q27684773-6F1A8FE5-7C16-4E4D-9631-FB8537DD13A8

Q27684773-EBFB8C64-F48C-41D9-B050-EC3029161C1E

P577

Q27684773-5FFBDAFD-F9E1-4423-B0B2-2FEDA533C3DB

P5875

Q27684773-6D0C1E1E-E127-4327-BAD0-7A6B7EE8A50D

P698

Q27684773-DFFA0AEC-591D-48E2-97F8-660D86F2F551

P932

Q27684773-6C2771AA-14B4-4288-B0F3-1B2FAE00DE6D

P3181

P356

PNAS.1410250111

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Structure of the eukaryotic tr ...... chanism for dissociating eIF4G

@en

P2093

Bertal H Aktas

http://www.w3.org/2001/XMLSchema#string

Eihab Kabha

http://www.w3.org/2001/XMLSchema#string

Evangelos Papadopoulos

http://www.w3.org/2001/XMLSchema#string

Gerhard Wagner

http://www.w3.org/2001/XMLSchema#string

Jose A Halperin

http://www.w3.org/2001/XMLSchema#string

Khuloud J Takrouri

http://www.w3.org/2001/XMLSchema#string

Michael Chorev

http://www.w3.org/2001/XMLSchema#string

Poornachandran Mahalingam

http://www.w3.org/2001/XMLSchema#string

Rafael E Luna

http://www.w3.org/2001/XMLSchema#string

Revital Yefidoff-Freedman

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation

PHENIX: a comprehensive Python-based system for macromolecular structure solution

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Improved methods for building protein models in electron density maps and the location of errors in these models

Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E

Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein

Inference of macromolecular assemblies from crystalline state

P304

E3187-95

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3906414

http://www.w3.org/2001/XMLSchema#string

P356

10.1073/PNAS.1410250111

http://www.w3.org/2001/XMLSchema#string

P407

P433

31

http://www.w3.org/2001/XMLSchema#string

P478

111

http://www.w3.org/2001/XMLSchema#string

P50

Haribabu Arthanari

Evripidis Gavathiotis

P577

2014-08-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

264125967

http://www.w3.org/2001/XMLSchema#string

P698

25049413

http://www.w3.org/2001/XMLSchema#string

P932

4128100

http://www.w3.org/2001/XMLSchema#string