Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions
about
At short telomeres Tel1 directs early replication and phosphorylates Rif1.Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complexRif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencingRegulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Macromolecular ab initio phasing enforcing secondary and tertiary structureAlternative arrangements of telomeric recognition sites regulate the binding mode of the DNA-binding domain of yeast Rap1.Regulation of Telomere Length Requires a Conserved N-Terminal Domain of Rif2 in Saccharomyces cerevisiae.Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA ReplicationRif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts.Role of the double-strand break repair pathway in the maintenance of genomic stability.Rif1 Regulates the Fate of DNA Entanglements during Mitosis.Biology of telomeres: lessons from budding yeast.Transcriptional outcome of telomere signalling.Telomere length regulation in budding yeasts.Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).How do telomeres and NHEJ coexist?Genome-wide studies of telomere biology in budding yeastStructural and biophysical characterization of murine rif1 C terminus reveals high specificity for DNA cruciform structures.Rif1 binds to G quadruplexes and suppresses replication over long distances.Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE.The mre11 A470 alleles influence the hereditability and the segregation of telosomes in Saccharomyces cerevisiae.Nuclear Architecture Organized by Rif1 Underpins the Replication-Timing Program.Structural Insights into Yeast Telomerase Recruitment to Telomeres.Structural and functional analyses of the mammalian TIN2-TPP1-TRF2 telomeric complex.Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends.Oligomer formation and G-quadruplex-binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture.Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.Budding yeast Rif1 binds to replication origins and protects DNA at blocked replication forks
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P2860
Rif1 and Rif2 shape telomere function and architecture through multivalent Rap1 interactions
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@ast
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@en
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@nl
type
label
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@ast
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@en
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@nl
prefLabel
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@ast
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@en
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@nl
P2093
P50
P3181
P1433
P1476
Rif1 and Rif2 shape telomere f ...... multivalent Rap1 interactions
@en
P2093
Andrea Scrima
Mahamadou Faty
Nicolas H Thomä
Seth M Rubin
Stefano Mattarocci
Tianlai Shi
P304
P3181
P356
10.1016/J.CELL.2013.05.007
P407
P577
2013-06-01T00:00:00Z