Rif1 binds to G quadruplexes and suppresses replication over long distances.
about
Effects of DNA supercoiling on chromatin architectureRif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts.Rif1 Regulates the Fate of DNA Entanglements during Mitosis.Mouse Rif1 is a regulatory subunit of protein phosphatase 1 (PP1).Effects of DNA supercoiling on chromatin architecture.The functions of the multi-tasking Pfh1Pif1 helicase.The chromatin environment shapes DNA replication origin organization and defines origin classes.The human mitochondrial transcription factor A is a versatile G-quadruplex binding protein.A G-quadruplex structure at the 5' end of the H19 coding region regulates H19 transcription.Establishment of expression-state boundaries by Rif1 and Taz1 in fission yeastHuman RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation.G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA helicaseInvestigating DNA supercoiling in eukaryotic genomes.Shelterin components mediate genome reorganization in response to replication stress.A triple stranded G-quadruplex formation in the promoter region of human myosin β(Myh7) gene.Identification of SLIRP as a G Quadruplex-Binding Protein.Silencing RIF1 decreases cell growth, migration and increases cisplatin sensitivity of human cervical cancer cells.Mms1 is an assistant for regulating G-quadruplex DNA structures.Oligomer formation and G-quadruplex-binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture.Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand.Replication timing and nuclear structure.Design, Synthesis and Biological Evaluation of New Substituted Diquinolinyl-Pyridine Ligands as Anticancer Agents by Targeting G-Quadruplex.Requirement or exclusion of inverted repeat sequences with cruciform-forming potential in Escherichia coli revealed by genome-wide analyses.The fission yeast Stn1-Ten1 complex limits telomerase activity via its SUMO-interacting motif and promotes telomeres replication.Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres.Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks.Recent advances in understanding DNA replication: cell type-specific adaptation of the DNA replication programRIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signalingBudding yeast Rif1 binds to replication origins and protects DNA at blocked replication forksRIF1 promotes human epithelial ovarian cancer growth and progression via activating human telomerase reverse transcriptase expression
P2860
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P2860
Rif1 binds to G quadruplexes and suppresses replication over long distances.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Rif1 binds to G quadruplexes and suppresses replication over long distances.
@en
type
label
Rif1 binds to G quadruplexes and suppresses replication over long distances.
@en
prefLabel
Rif1 binds to G quadruplexes and suppresses replication over long distances.
@en
P2093
P2860
P356
P1476
Rif1 binds to G quadruplexes and suppresses replication over long distances
@en
P2093
Claire Renard-Guillet
Hisao Masai
Kazuo Nagasawa
Keisuke Iida
Koji Masuda
Naoko Kakusho
Rino Fukatsu
Seiji Matsumoto
Yutaka Kanoh
P2860
P2888
P304
P356
10.1038/NSMB.3102
P577
2015-10-05T00:00:00Z