Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis
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Review: basics of drug development in rheumatologyDiscovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.Quantitative structure-activity relationship study on BTK inhibitors by modified multivariate adaptive regression spline and CoMSIA methods.The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.Investigational Bruton's tyrosine kinase inhibitors for the treatment of rheumatoid arthritis.Bioactivation of cyclopropyl rings by P450: an observation encountered during the optimisation of a series of hepatitis C virus NS5B inhibitors.Bruton's Tyrosine Kinase Deficiency Inhibits Autoimmune Arthritis in Mice but Fails to Block Immune Complex-Mediated Inflammatory Arthritis.
P2860
Q28083593-A7B92753-0219-4C21-AD24-289E73676C71Q33786371-C5F05F72-33ED-41E4-BE06-7A22D1A87D0BQ38444266-B50C22B4-4C71-4878-98B3-25329C17BD60Q38728631-32315993-802F-4371-8ABB-ED252C40EBADQ38826405-5B8DA365-F821-4BDB-AEDD-622E6AFA51ABQ45324155-11C030F3-7B8D-40CE-A568-459E8288FD33Q46333548-8D9E27F3-FADB-40AD-8505-E62FE6DE40F8
P2860
Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis
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2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Structure-based drug design of ...... atment of rheumatoid arthritis
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Structure-based drug design of ...... atment of rheumatoid arthritis
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Structure-based drug design of ...... atment of rheumatoid arthritis
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type
label
Structure-based drug design of ...... atment of rheumatoid arthritis
@ast
Structure-based drug design of ...... atment of rheumatoid arthritis
@en
Structure-based drug design of ...... atment of rheumatoid arthritis
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prefLabel
Structure-based drug design of ...... atment of rheumatoid arthritis
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Structure-based drug design of ...... atment of rheumatoid arthritis
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Structure-based drug design of ...... atment of rheumatoid arthritis
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P2093
P356
P1476
Structure-based drug design of ...... atment of rheumatoid arthritis
@en
P2093
Buelent Kocer
Dana Davis
David M Goldstein
Hasim Zecic
Jaehyeon Park
Joel McIntosh
Joshua P Taygerly
Junbae Hong
Keshab Sarma
P356
10.1021/JM500305P
P407
P577
2015-01-08T00:00:00Z