Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties. - Wikidata - wikimedia - TriplyDB

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.

http://www.wikidata.org/entity/Q33786371

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Drug-Target Kinetics in Drug Discovery.

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P2860

Discovery of Potent and Selective Tricyclic Inhibitors of Bruton's Tyrosine Kinase with Improved Druglike Properties.

http://www.wikidata.org/entity/Q33786371

description

2017 nî lūn-bûn

@nan

2017 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2017 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2017年の論文

@ja

2017年論文

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2017年論文

@zh-hant

2017年論文

@zh-hk

2017年論文

@zh-mo

2017年論文

@zh-tw

2017年论文

@wuu

name

Discovery of Potent and Select ...... Improved Druglike Properties.

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Discovery of Potent and Select ...... Improved Druglike Properties.

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type

label

Discovery of Potent and Select ...... Improved Druglike Properties.

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Discovery of Potent and Select ...... Improved Druglike Properties.

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prefLabel

Discovery of Potent and Select ...... Improved Druglike Properties.

@ast

Discovery of Potent and Select ...... Improved Druglike Properties.

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ACSMEDCHEMLETT.7B00103

P1433

ACS Medicinal Chemistry Letters

P1476

Discovery of Potent and Select ...... Improved Druglike Properties.

@en

P2093

Aaron Schmitt

http://www.w3.org/2001/XMLSchema#string

Adam R Johnson

http://www.w3.org/2001/XMLSchema#string

Arna Katewa

http://www.w3.org/2001/XMLSchema#string

Charles Eigenbrot

http://www.w3.org/2001/XMLSchema#string

Daniel F Ortwine

http://www.w3.org/2001/XMLSchema#string

Fusheng Zhou

http://www.w3.org/2001/XMLSchema#string

Harvey Wong

http://www.w3.org/2001/XMLSchema#string

Heleen Scheerens

http://www.w3.org/2001/XMLSchema#string

Huiyong Hu

http://www.w3.org/2001/XMLSchema#string

Jacob Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis

Potent and selective Bruton's tyrosine kinase inhibitors: discovery of GDC-0834

Discovery of highly potent and selective Bruton's tyrosine kinase inhibitors: Pyridazinone analogs with improved metabolic stability

Small Molecule Reversible Inhibitors of Bruton's Tyrosine Kinase (BTK): Structure-Activity Relationships Leading to the Identification of 7-(2-Hydroxypropan-2-yl)-4-[2-methyl-3-(4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-9H-carbazole-1-carboxamide (BM

Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations

Bruton's Tyrosine Kinase is involved in innate and adaptive immunity

The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective.

Bruton's TK inhibitors: structural insights and evolution of clinical candidates.

Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis.

Bruton's tyrosine kinase inhibitors: approaches to potent and selective inhibition, preclinical and clinical evaluation for inflammatory diseases and B cell malignancies.

P304

608-613

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scholarly article

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10.1021/ACSMEDCHEMLETT.7B00103

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6

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8

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James J Crawford

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2017-05-03T00:00:00Z

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28626519

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5467183

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