Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme
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Replacement of water molecules in a phosphate binding site by furanoside-appended lin-benzoguanine ligands of tRNA-guanine transglycosylase (TGT)The use of thermodynamic and kinetic data in drug discovery: decisive insight or increasing the puzzlement?Soaking suggests "alternative facts": Only co-crystallization discloses major ligand-induced interface rearrangements of a homodimeric tRNA-binding protein indicating a novel mode-of-inhibitionApplication of isothermal titration calorimetry as a tool to study natural product interactions.Molecular recognition in chemical and biological systems.Applications of isothermal titration calorimetry - the research and technical developments from 2011 to 2015.Molecular imaging of fibrosis using a novel collagen-binding peptide labelled with 99mTc on SPECT/CT.An Immucillin-Based Transition-State-Analogous Inhibitor of tRNA-Guanine Transglycosylase (TGT).
P2860
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P2860
Chasing protons: how isothermal titration calorimetry, mutagenesis, and pKa calculations trace the locus of charge in ligand binding to a tRNA-binding enzyme
description
2014 nî lūn-bûn
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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@ast
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@en
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@nl
type
label
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@ast
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@en
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@nl
altLabel
Chasing Protons: How Isotherma ...... nding to a tRNA-Binding Enzyme
@en
prefLabel
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@ast
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@en
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@nl
P2093
P50
P356
P1476
Chasing protons: how isotherma ...... nding to a tRNA-binding enzyme
@en
P2093
Andreas Heine
Christoph Hohn
Luzi Jakob Barandun
Manuel Neeb
P304
P356
10.1021/JM500401X
P407
P577
2014-07-10T00:00:00Z