A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity
about
Utility of the dual-specificity protein kinase TTK as a therapeutic target for intrahepatic spread of liver cancerMps1 inhibitors synergise with low doses of taxanes in promoting tumour cell death by enhancement of errors in cell division.Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N-(2-Ethoxy-4-(4-methyl-4 H-1,2,4-triazol-3-yl)phenyl)-6-methyl- N-neopentyl
P2860
A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity
description
2015 nî lūn-bûn
@nan
2015 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
A unique hinge binder of extre ...... ibitors with cellular activity
@ast
A unique hinge binder of extre ...... ibitors with cellular activity
@en
A unique hinge binder of extre ...... ibitors with cellular activity
@nl
type
label
A unique hinge binder of extre ...... ibitors with cellular activity
@ast
A unique hinge binder of extre ...... ibitors with cellular activity
@en
A unique hinge binder of extre ...... ibitors with cellular activity
@nl
prefLabel
A unique hinge binder of extre ...... ibitors with cellular activity
@ast
A unique hinge binder of extre ...... ibitors with cellular activity
@en
A unique hinge binder of extre ...... ibitors with cellular activity
@nl
P2093
P3181
P1476
A unique hinge binder of extre ...... ibitors with cellular activity
@en
P2093
Eiichi Kojima
Genta Tadano
Hidenori Yoshizawa
Hitoshi Murai
Keiji Dohi
Kenichi Higashino
Makiko Inoue
Masahiro Maeda
Masayo Higaki
Motofumi Iguchi
P304
P3181
P356
10.1016/J.BMC.2015.02.042
P407
P577
2015-05-01T00:00:00Z