STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition - Wikidata - wikimedia - TriplyDB

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

http://www.wikidata.org/entity/Q27701410

about

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system Diversity of CRISPR-Cas immune systems and molecular machines Minimizing off-Target Mutagenesis Risks Caused by Programmable Nucleases Current and future prospects for CRISPR-based tools in bacteria The New State of the Art: Cas9 for Gene Activation and Repression Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow.Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage The crystal structure of Cpf1 in complex with CRISPR RNA A CRISPR toolbox to study virus-host interactions Striking Plasticity of CRISPR-Cas9 and Key Role of Non-target DNA, as Revealed by Molecular Simulations.Significant enhancement of fatty acid composition in seeds of the allohexaploid, Camelina sativa, using CRISPR/Cas9 gene editing.Mechanism of duplex DNA destabilization by RNA-guided Cas9 nuclease during target interrogation.Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation.Disabling Cas9 by an anti-CRISPR DNA mimic High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.Structure and Engineering of Francisella novicida Cas9.The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA.Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors.Applications of CRISPR technologies in research and beyond.Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA Structure and specificity of the RNA-guided endonuclease Cas9 during DNA interrogation, target binding and cleavage Single-Stranded DNA Cleavage by Divergent CRISPR-Cas9 Enzymes In Vitro CRISPR/Cas9 System for Efficient Targeted DNA Editing.Crystal Structure of Staphylococcus aureus Cas9 DNA-binding-domain fusions enhance the targeting range and precision of Cas9.Synthetic CRISPR RNA-Cas9-guided genome editing in human cells Expanding the CRISPR imaging toolset with Staphylococcus aureus Cas9 for simultaneous imaging of multiple genomic loci.Conformational control of DNA target cleavage by CRISPR-Cas9.Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli Nucleosome breathing and remodeling constrain CRISPR-Cas9 function.Optimization of genome editing through CRISPR-Cas9 engineering CRISPR-Cas9 nuclear dynamics and target recognition in living cells.Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease.Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence.Elasticity of the transition state for oligonucleotide hybridization.CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations.Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.CRISPR-Cas9 Mediated DNA Unwinding Detected Using Site-Directed Spin Labeling.CRISPR-Cas orthologues and variants: optimizing the repertoire, specificity and delivery of genome engineering tools.

P2860

Q24669821-3F533E65-714D-41A7-97B7-AAF0AE75B9D9 Q26778564-D0F44FB9-6BDC-4F83-9EF7-A5E1ADC6412C Q26778992-301CBE40-7C6A-4C5B-A8F9-D228119F34F6 Q26783837-AAA5E25C-B825-4591-97C4-31E6FA686DA3 Q26787037-59DA6E7F-3A5D-4956-A147-9BF005C2F468 Q27313598-5BC647A6-D9A1-43BC-AE04-83ACE88B1C38 Q27703932-F2FFF097-0AF3-43B6-B2BA-873CD3993077 Q27704663-38152F65-2EE3-4CF6-A531-086B01D16DAD Q29994612-EC89FDF1-D2C8-4D58-8887-97EF9FA8ECAF Q30826748-7ABEF953-67AF-48C6-9EA3-740B6D6FE8C9 Q33586055-29CAABFA-FA83-49F2-8DDF-8F0D26CAECBD Q33737900-64432807-8F65-45D8-A002-52920EB63B49 Q33861368-B70390EB-9F73-4288-8322-CF9E5D17CB6D Q33898855-C2B29B9A-2AB6-4229-ACC9-7F36CFEBA888 Q34507554-5807FA52-4B29-4CA4-A476-2A06DF8C34AD Q34514052-6D09DD57-CDA2-45FD-B902-96C5543E5D35 Q34522844-855E57FB-B9BB-4988-8893-662497B615AA Q34524602-9EFE3BAA-C791-49A4-B7EC-332EFA37F265 Q34538256-5CEAFCBA-17EF-479D-8B1A-FA8DD74BB8BF Q34539796-F65DF197-6C6A-4ED1-B4CD-42AB03C88401 Q35999041-5CF8D972-0923-46E8-A0A0-BB3C7E7F9F31 Q36160691-EE2466E9-4D67-43D9-AD25-3C3FE68B60C6 Q36258984-4C49CA4C-C126-4AB6-8334-3AA17E492E02 Q36318978-FBDFE46B-AD01-4169-BEFB-508270AFD5C6 Q36348284-033E9654-649E-4FF7-A7A0-DF9487D1DEB6 Q36372381-DA11DE75-73CC-481E-A863-E11DFD77DC55 Q36419827-00ED2979-4A96-49D2-9AEA-5F5A9B4B8C64 Q36870491-6E8FCE5A-CF2F-409D-9EFD-75CFA2E4ED14 Q36879255-A8421612-B024-4FFB-A695-F6116E145F8A Q36914633-7EFC765F-3F5E-4AAF-B3DB-AE2C57FD2E3C Q36936033-51E41F49-D80B-4F4F-9491-3CD357EF84C6 Q37052485-B4E1C1FB-BE15-46B2-B426-A3C9EF7F4377 Q37216431-D032D62C-328E-4356-9EFD-8DA252A2898A Q37396156-E997EB23-4EB8-422A-95F3-C760DCCD0871 Q37591346-28600BC0-F0CB-43CA-A617-E1D1790EECB2 Q37649476-12EE879C-6F1D-42CA-9911-EF47F5302340 Q38666403-7590DCF2-E89B-4B63-B8C9-05B46F2D9B3C Q38682882-0BEB7E3C-2E84-4558-AA15-A541BBC9671C Q38691551-59095302-8B4E-4EBB-A928-7F49952E445B Q38716317-00EF25F1-6528-45BA-803B-DBE4557CF0F6

P2860

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

http://www.wikidata.org/entity/Q27701410

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@ast

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@en

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@nl

type

label

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@ast

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@en

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@nl

prefLabel

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@ast

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@en

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@nl

P1433

Q27701410-8EA253C9-CF09-4D53-BFF6-DEBA8860A255

P1476

Q27701410-38EFB012-4191-4674-A69A-DE140C0A059D

P2093

Q27701410-3E6A2B73-E728-499E-A8AB-F559F1EA800D

Q27701410-6D7AC300-1E99-4A7E-BF40-9F9889E2EB94

Q27701410-F7F13C6E-7D8E-434A-A9D1-3D1059D9DF06

P2860

Q27701410-0014821F-C124-43A0-8EC4-DDB32DFD1A04

Q27701410-06353DE9-8A25-4FBD-81C1-C8BFE88CA8B0

Q27701410-08487E68-F5FC-43DB-8B89-D2DACEF99A18

Q27701410-0C15119B-F3E7-45C8-9A8D-D826030A5DA9

Q27701410-12E79B2B-0E92-44CA-B9E9-B4938B6EAFC4

Q27701410-13EF5A16-43A7-421C-B828-8C09403A06DC

Q27701410-17C1918C-ABB5-42B4-8203-4543AF92CE75

Q27701410-186A05D7-68C4-4DFF-A445-B7C96843593F

Q27701410-24188E8C-FA50-44B1-AE0A-7FECBBC4849C

Q27701410-31C63948-A57F-45B7-9C82-5F2F46FCA2E3

P304

Q27701410-8D71A8CB-49DE-4366-B0F4-913EB343969D

P31

Q27701410-E70CD69C-94C2-4622-B674-5C27E3ABFFB9

P3181

Q27701410-3700F1DF-3E58-456C-A681-9E16ACF02258

P356

Q27701410-7C6A8B02-A98D-4CAF-B993-0A8770F0CC99

P407

Q27701410-0EF27917-CE4C-4E4A-8F84-BE3135CF8FCF

P433

Q27701410-F6694027-C936-42A4-92F3-4684D7CD8052

P478

Q27701410-EF1DC9D6-3B08-46B8-976D-C877039B0AA1

P50

Q27701410-240A62E4-C22E-4340-9DCE-7FC6A37CF11A

Q27701410-8A2E6A9F-580A-4458-9E70-14C5F1BA98A2

P577

Q27701410-7A5E76F5-6655-4455-AB2A-30AEC203F722

P5875

Q27701410-E0E9FF5F-7499-45EE-9492-293B20BB8F0E

P698

Q27701410-1AD9D1C1-0069-4D28-B7D6-BA45FF946BE7

P3181

P356

SCIENCE.AAB1452

P1433

P1476

STRUCTURAL BIOLOGY. A Cas9-guide RNA complex preorganized for target DNA recognition

@en

P2093

Fuguo Jiang

http://www.w3.org/2001/XMLSchema#string

Kaihong Zhou

http://www.w3.org/2001/XMLSchema#string

Linlin Ma

http://www.w3.org/2001/XMLSchema#string

P2860

In vitro reconstitution of the human RISC-loading complex

Multiplex genome engineering using CRISPR/Cas systems

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

MolProbity: all-atom structure validation for macromolecular crystallography

PHENIX: a comprehensive Python-based system for macromolecular structure solution

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

The Crystal Structure of Human Argonaute2

The Structure of Human Argonaute-2 in Complex with miR-20a

P304

1477-81

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

882070

http://www.w3.org/2001/XMLSchema#string

P356

10.1126/SCIENCE.AAB1452

http://www.w3.org/2001/XMLSchema#string

P407

P433

6242

http://www.w3.org/2001/XMLSchema#string

P478

348

http://www.w3.org/2001/XMLSchema#string

P50

Jennifer Doudna

P577

2015-06-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

279301967

http://www.w3.org/2001/XMLSchema#string

P698

26113724

http://www.w3.org/2001/XMLSchema#string