The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions
about
Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situHIV type 1 Gag as a target for antiviral therapyESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formationVirus maturation as a new HIV-1 therapeutic targetHIV-1 protease and reverse transcriptase control the architecture of their nucleocapsid partnerCryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus ArchitectureThree-Dimensional Structural Characterization of HIV-1 Tethered to Human Cells.Distribution and Redistribution of HIV-1 Nucleocapsid Protein in Immature, Mature, and Integrase-Inhibited Virions: a Role for Integrase in MaturationNative immunogold labeling of cell surface proteins and viral glycoproteins for cryo-electron microscopy and cryo-electron tomography applicationsProtease cleavage leads to formation of mature trimer interface in HIV-1 capsidProton-driven Assembly of the Rous Sarcoma Virus Capsid Protein Results in the Formation of Icosahedral ParticlesElectron tomography of cells3D visualization of HIV virions by cryoelectron tomographyRole of the SP2 domain and its proteolytic cleavage in HIV-1 structural maturation and infectivityPrimate TRIM5 proteins form hexagonal nets on HIV-1 capsids.Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly.HIV/AIDS epidemiology, pathogenesis, prevention, and treatmentInfluenza virus pleiomorphy characterized by cryoelectron tomographyDesign of in vitro symmetric complexes and analysis by hybrid methods reveal mechanisms of HIV capsid assemblyThe structural biology of HIV assembly.Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells.Architecture of a nascent viral fusion pore.Automated tracing of filaments in 3D electron tomography reconstructions using Sculptor and Situs.Developing a denoising filter for electron microscopy and tomography data in the cloud.Maturation of the HIV-1 core by a non-diffusional phase transition.Analysis of human T-cell leukemia virus type 1 particles by using cryo-electron tomography.TOMOBFLOW: feature-preserving noise filtering for electron tomography.Effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and human immunodeficiency virus.Novel approaches to inhibiting HIV-1 replication.Cryo electron tomography of native HIV-1 budding sites.Structural analysis of HIV-1 maturation using cryo-electron tomography.Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid.Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.Biophysical analysis of HTLV-1 particles reveals novel insights into particle morphology and Gag stochiometry.HIV-1 assembly: viral glycoproteins segregate quantally to lipid rafts that associate individually with HIV-1 capsids and virionsHIV-1 maturation inhibitor bevirimat stabilizes the immature Gag latticeBiophysical characterization of the feline immunodeficiency virus p24 capsid protein conformation and in vitro capsid assembly.A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsidAntiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domainDeterminants of the HIV-1 core assembly pathway.
P2860
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P2860
The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions
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2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2006 թվականի հունվարին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
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2006年論文
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2006年論文
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2006年論文
@zh-mo
2006年論文
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2006年论文
@wuu
name
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@ast
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@en
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@nl
type
label
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@ast
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@en
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@nl
prefLabel
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@ast
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@en
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@nl
P2093
P50
P3181
P1433
P1476
The Mechanism of HIV-1 Core As ...... tructions of Authentic Virions
@en
P2093
Bärbel Glass
Friedrich Förster
Stephen D. Fuller
P3181
P356
10.1016/J.STR.2005.09.010
P577
2006-01-01T00:00:00Z