Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
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Myristoylation-dependent replication and assembly of human immunodeficiency virus 1Molecular mechanisms for the conversion of zymogens to active proteolytic enzymesInhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particlesImproved prediction of HIV-1 protease-inhibitor binding energies by molecular dynamics simulationsCharacterization of the protease domain of Rice tungro bacilliform virus responsible for the processing of the capsid protein from the polyproteinComputational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β -SecretaseIn silico prediction of mutant HIV-1 proteases cleaving a target sequenceFlavivirus enzyme-substrate interactions studied with chimeric proteinases: identification of an intragenic locus important for substrate recognitionThe Role of Medical Structural Genomics in Discovering New Drugs for Infectious Diseases1.9 A x-ray study shows closed flap conformation in crystals of tethered HIV-1 PROptimization of P1-P3 groups in symmetric and asymmetric HIV-1 protease inhibitorsNucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modelingInsights from Atomic-Resolution X-Ray Structures of Chemically Synthesized HIV-1 Protease in Complex with InhibitorsContribution of the 80s loop of HIV-1 protease to the multidrug-resistance mechanism: crystallographic study of MDR769 HIV-1 protease variantsSynthesis, X-ray Analysis, and Biological Evaluation of a New Class of Stereopure Lactam-Based HIV-1 Protease InhibitorsX-ray crystallographic structure of a complex between a synthetic protease of human immunodeficiency virus 1 and a substrate-based hydroxyethylamine inhibitorJoint X-ray/Neutron Crystallographic Study of HIV-1 Protease with Clinical Inhibitor Amprenavir: Insights for Drug DesignA plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active siteStructure of HOE/BAY 793 complexed to human immunodeficiency virus (HIV-1) protease in two different crystal forms--structure/function relationship and influence of crystal packingPrinciples of protein-protein interactionsThe aspartic proteasesIn vitro inhibition of HIV-1 proteinase by ceruleninCopper inhibits the protease from human immunodeficiency virus 1 by both cysteine-dependent and cysteine-independent mechanismsStructure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 proteaseAn inhibitor of the protease blocks maturation of human and simian immunodeficiency viruses and spread of infectionIncorporation of 12-methoxydodecanoate into the human immunodeficiency virus 1 gag polyprotein precursor inhibits its proteolytic processing and virus production in a chronically infected human lymphoid cell lineInhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitorsCharacterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitorAntiretroviral activities of protease inhibitors against murine leukemia virus and simian immunodeficiency virus in tissue cultureEfficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitroA look inside HIV resistance through retroviral protease interaction mapsVerification of protein structures: patterns of nonbonded atomic interactionsRecent developments in inhibiting cysteine and serine proteases.Ongoing trials in HIV protease inhibitors.Point mutations and sequence variability in proteins: redistributions of preexisting populations.Overview of protein structural and functional folds.Protein crystallography for non-crystallographers, or how to get the best (but not more) from published macromolecular structures.Protein crystallography for aspiring crystallographers or how to avoid pitfalls and traps in macromolecular structure determination.Anatomy of protein pockets and cavities: measurement of binding site geometry and implications for ligand design
P2860
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P2860
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
description
1989 nî lūn-bûn
@nan
1989 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@ast
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@en
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@nl
type
label
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@ast
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@en
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@nl
prefLabel
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@ast
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@en
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@nl
P2093
P356
P1433
P1476
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
@en
P2093
B M McKeever
J C Heimbach
J P Springer
P M Fitzgerald
W K Herber
P2888
P304
P356
10.1038/337615A0
P407
P577
1989-02-16T00:00:00Z
P6179
1037836841