Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
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Structural and biophysical analyses of the skeletal dihydropyridine receptor β subunit β1a reveal critical roles of domain interactions for stability.Structure-based assessment of disease-related mutations in human voltage-gated sodium channels.Biological cryo-electron microscopy in ChinaProteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.Physiology and Evolution of Voltage-Gated Calcium Channels in Early Diverging Animal Phyla: Cnidaria, Placozoa, Porifera and Ctenophora.Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET.The Auxiliary Calcium Channel Subunit α2δ4 Is Required for Axonal Elaboration, Synaptic Transmission, and Wiring of Rod Photoreceptors.Structure of IP3R channel: high-resolution insights from cryo-EM.Proteolytic cleavage of the hydrophobic domain in the CaVα2δ1 subunit improves assembly and activity of cardiac CaV1.2 channels.Injury-induced maladaptation and dysregulation of calcium channel α2 δ subunit proteins and its contribution to neuropathic pain development.TMBIM-mediated Ca2+ homeostasis and cell death.The chemical basis for electrical signaling.Crystal structures of claudins: insights into their intermolecular interactions.On the structure and mechanism of two-pore channels.Domain-to-domain coupling in voltage-sensing phosphatase.Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially.Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.Calmodulin limits pathogenic Na+ channel persistent current.LRP1 influences trafficking of N-type calcium channels via interaction with the auxiliary α2δ-1 subunit.Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.Key role of segment IS4 in Cav1.2 inactivation: link between activation and inactivation.Negatively charged residues in the first extracellular loop of the L-type CaV1.2 channel anchor the interaction with the CaVα2δ1 auxiliary subunit.Molecular basis of AKAP79 regulation by calmodulin.Identification of a novel cAMP dependent protein kinase A phosphorylation site on the human cardiac calcium channel.The voltage sensor of excitation-contraction coupling in mammals: Inactivation and interaction with Ca2.Inactivation of KCNQ1 potassium channels reveals dynamic coupling between voltage sensing and pore opening.Calcium channel structures come of age.Lipid environment of membrane proteins in cryo-EM based structural analysis.Molecular mechanisms and physiological relevance of RGK proteins in the heart.Altered spontaneous calcium signaling of in situ chondrocytes in human osteoarthritic cartilage.Rhabdomyolysis and fluctuating asymptomatic hyperCKemia associated with CACNA1S variant.The structural basis of ryanodine receptor ion channel function.Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.Conservation and variability of the pore-lining helices in P-loop channels.A perspective on Na and K channel inactivation.Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective.Molecular moieties masking Ca2+-dependent facilitation of voltage-gated Cav2.2 Ca2+ channels.Cross talk between β subunits, intracellular Ca2+ signaling, and SNAREs in the modulation of CaV 2.1 channel steady-state inactivation.Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.
P2860
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P2860
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
description
2016 nî lūn-bûn
@nan
2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Structure of the voltage-gated calcium channel Ca<sub>v</sub>1.1 at 3.6 Å resolution
@nl
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@ast
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@en
type
label
Structure of the voltage-gated calcium channel Ca<sub>v</sub>1.1 at 3.6 Å resolution
@nl
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@ast
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@en
prefLabel
Structure of the voltage-gated calcium channel Ca<sub>v</sub>1.1 at 3.6 Å resolution
@nl
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@ast
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
@en
P2093
P3181
P356
P1433
P1476
Structure of the voltage-gated ...... sub>1.1 at 3.6 Å resolution
@en
P2093
Jianping Wu
Mengqiu Dong
Qiang Zhou
Xingyang Qian
Zhangqiang Li
P2888
P304
P3181
P356
10.1038/NATURE19321
P407
P50
P577
2016-08-31T00:00:00Z
P6179
1048556285