The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor
about
Structure of porcine pancreatic elastase complexed with FR901277, a novel macrocyclic inhibitor of elastases, at 1.6 A resolutionThe refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationshipsThe refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segmentThe 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificitiesStructural basis of substrate specificity in the serine proteasesSelection of human elastase inhibitors from a conformationally constrained combinatorial peptide library.Design, synthesis and evaluation of biomimetic affinity ligands for elastases.Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.Structural and energetic determinants of the S1-site specificity in serine proteases.Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases.Phosphatidylinositol 4-kinase III beta is a target of enviroxime-like compounds for antipoliovirus activity.Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors.The structure of thrombin, a chameleon-like proteinase.Preliminary crystallographic study of two cuticle-degrading proteases from the nematophagous fungi Lecanicillium psalliotae and Paecilomyces lilacinus.Targeting COPD: advances on low-molecular-weight inhibitors of human neutrophil elastase.Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures.Inhibition of human leucocyte elastase by ursolic acid. Evidence for a binding site for pentacyclic triterpenes.Potential of pyrazolooxadiazinone derivatives as serine protease inhibitors.Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sites.A BODIPY-Tagged Phosphono Peptide as Activity-Based Probe for Human Leukocyte Elastase.Novel Mechanism of Inhibition of Elastase by β-Lactams Is Defined by Two Inhibitor Crystal ComplexesEarthworm Protease
P2860
Q27621920-4E6DCC9C-3B6A-4A91-BA07-1E875B20ADFFQ27642041-E3FB15BB-DE97-4BD6-98D4-9495D55FCD72Q27700069-FCE7D40A-B0DF-4761-94C3-F922CA04FCA1Q27733782-D44668F4-B0AC-4464-9D2B-28FDD6E2643AQ29619675-B102AD01-998C-4734-98D7-524562F8546EQ30812768-4054BF10-39EF-4704-987F-12EA7F1215F2Q31835096-A91086D1-4F7D-4399-8A72-3106B8EB1ACCQ33348995-6865B80F-8638-411D-B4C4-43D639E30BFBQ33548213-FCB25470-0899-45DE-AC82-676874A09DADQ34149948-C7131041-25D5-498F-A45A-A0E61BD259FDQ34742005-E270D8AA-F5E1-4E3F-AF52-EB224C5C2057Q35598518-1E976478-B756-41C2-95B3-C27A8CE91679Q36126935-CD47AA34-8EFF-4108-B0AC-62EBC21AEC68Q37115494-4D886B85-0927-4179-8E1C-BC584490241BQ37890978-F4554A48-17A1-424F-AC00-196DFB56E02BQ38850115-4D3163CA-F824-433C-AEE3-143A16B08DE2Q42814754-90C17843-1BDB-4665-9183-D88A3EDA88EEQ42862107-FB883394-D502-44DE-B07C-C3661CF7BA50Q43702157-6FB39E36-EC4C-41B5-9A17-504441D20915Q44257223-72079879-5304-44C2-AB33-2013A122BBCFQ52579075-CF3ECF50-CBCC-4E37-A61C-16FFAB57E1B0Q57003687-23D7BAA4-6132-43AA-B2FF-2E9C104AFA83Q58650317-352CB13C-B7EC-4DAE-A7B0-5CACE2D23808
P2860
The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor
description
1988 nî lūn-bûn
@nan
1988 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
name
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@ast
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@en
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@nl
type
label
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@ast
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@en
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@nl
prefLabel
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@ast
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@en
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@nl
P2093
P2860
P1433
P1476
The refined 2.3 A crystal stru ...... chloromethyl ketone inhibitor
@en
P2093
P2860
P304
P356
10.1016/0014-5793(88)80118-2
P407
P577
1988-07-18T00:00:00Z