Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G. Inhibition with peptide chloromethyl ketones.
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Neutrophil elastase, an acid-independent serine protease, facilitates reovirus uncoating and infection in U937 promonocyte cells.The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitorStructural elucidation of the N- and O-glycans of human apolipoprotein(a): role of o-glycans in conferring protease resistanceSimilarities between human and rat leukocyte elastase and cathepsin GCell-layer-associated proteolytic cleavage of the telopeptides of type I collagen in fibroblast cultureNeutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastaseThe synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinasesRecent developments in inhibiting cysteine and serine proteases.Structures of human proteinase 3 and neutrophil elastase--so similar yet so different.A serine peptidase responsible for the inactivation of endogenous cholecystokinin in brain.The specificity of macrophage elastase on the insulin B-chain.Mechanical properties of the extracellular matrix of the aorta studied by enzymatic treatments.Degradation of fibrin and elastin by intact human alveolar macrophages in vitro. Characterization of a plasminogen activator and its role in matrix degradationEffects of neutrophil elastase and other proteases on porcine aortic endothelial prostaglandin I2 production, adenine nucleotide release, and responses to vasoactive agents.Plasma levels of elastase-specific fibrinopeptides correlate with proteinase inhibitor phenotype. Evidence for increased elastase activity in subjects with homozygous and heterozygous deficiency of alpha 1-proteinase inhibitorGoblet cell hyperplasia in large intrapulmonary airways after intratracheal injection of cathepsin B into hamsters.Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes.Neutral protease secretion by human monocytes. Effect of surface-bound immune complexes.Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.Elastase-mediated fibrinogenolysis by chemoattractant-stimulated neutrophils occurs in the presence of physiologic concentrations of antiproteinasesElastase and cathepsin G activities are present in immature bone marrow neutrophils and absent in late marrow and circulating neutrophils of beige (Chediak-Higashi) miceInhibition of proteolytic activity of poliovirus and rhinovirus 2A proteinases by elastase-specific inhibitors.Oxidative regulation of neutrophil elastase-alpha-1-proteinase inhibitor interactionsPurification and characterization of a human neutrophil neutral protease. The neutral peptide-generating protease.Albumin microspheres as carrier of an inhibitor of leukocyte elastase: potential therapeutic agent for emphysema.Cleavage of the membrane precursor for transforming growth factor alpha is a regulated process.Detection and partial characterization of a chymostatin-sensitive endopeptidase in transformed fibroblasts.Recombinant C1 inhibitor P5/P3 variants display resistance to catalytic inactivation by stimulated neutrophils.Mechanisms of disruption of the articular cartilage surface in inflammation. Neutrophil elastase increases availability of collagen type II epitopes for binding with antibody on the surface of articular cartilage.Development of an assay for in vivo human neutrophil elastase activity. Increased elastase activity in patients with alpha 1-proteinase inhibitor deficiencyModified RNA sequence pools for in vitro selection.Cleavage and inactivation of Factor IX by granulocyte elastase.Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachment.Elastase of U-937 monocytelike cells. Comparisons with elastases derived from human monocytes and neutrophils and murine macrophagelike cells.Synthetic inhibitors of elastase.Comparison of live human neutrophil and alveolar macrophage elastolytic activity in vitro. Relative resistance of macrophage elastolytic activity to serum and alveolar proteinase inhibitorsElastase-like enzymes in human neutrophils localized by ultrastructural cytochemistryAntiproteases modulate bronchial epithelial cell responses to endotoxin.Cathepsin G is a strong platelet agonist released by neutrophils.Activation of human platelets by C5a-stimulated neutrophils: a role for cathepsin G.
P2860
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P2860
Specificity of porcine pancreatic elastase, human leukocyte elastase and cathepsin G. Inhibition with peptide chloromethyl ketones.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh-hant
name
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@en
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@nl
type
label
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@en
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@nl
prefLabel
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@en
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@nl
P2093
P1476
Specificity of porcine pancrea ...... peptide chloromethyl ketones.
@en
P2093
A D Harley
B F Gupton
J C Powers
R J Whitley
P304
P356
10.1016/0005-2744(77)90203-0
P577
1977-11-01T00:00:00Z