Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product
about
Structural evolution of the protein kinase-like superfamilyThe crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition.Effect of mutating the regulatory phosphoserine and conserved threonine on the activity of the expressed catalytic domain of Acanthamoeba myosin I heavy chain kinaseThe structure of phosphorylase kinase holoenzyme at 9.9 angstroms resolution and location of the catalytic subunit and the substrate glycogen phosphorylaseEffects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activitySpecific chemical and structural damage to proteins produced by synchrotron radiationStructure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitorCrystal structure of the catalytic domain of the PknB serine/threonine kinase from Mycobacterium tuberculosisStructural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibitionCrystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125Crystal Structure of the Ca2+/Calmodulin-dependent Protein Kinase Kinase in Complex with the Inhibitor STO-609Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitorsThe structure of dimeric ROCK I reveals the mechanism for ligand selectivityConservation, variability and the modeling of active protein kinasesMass Spectrometric Analysis of Surface-Exposed Regions in the Hexadecameric Phosphorylase Kinase ComplexOverview of protein structural and functional folds.Phosphate binding sites identification in protein structures.Structural trees for protein superfamilies.Substrate and docking interactions in serine/threonine protein kinasesStructural, thermodynamic, and kinetic effects of a phosphomimetic mutation in dynein light chain LC8.Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002.Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.Genetics of dark skin in mice.Structure and location of the regulatory β subunits in the (αβγδ)4 phosphorylase kinase complex.Ca(2+)/calmodulin-dependent protein kinases.Structural studies on the regulation of Ca2+/calmodulin dependent protein kinase IIIn Silico characterization of phosphorylase kinase: evidence for an alternate intronic polyadenylation site in PHKG1.Activation of protein kinase PKR requires dimerization-induced cis-phosphorylation within the activation loop.The calmodulin-binding domain of the catalytic gamma subunit of phosphorylase kinase interacts with its inhibitory alpha subunit: evidence for a Ca2+ sensitive network of quaternary interactions.Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: the role of water molecules examined.In vivo activation of recombinant cAPK catalytic subunit active site mutants by coexpression of the wild-type enzyme, evidence for intermolecular cotranslational phosphorylation.Bypass of Activation Loop Phosphorylation by Aspartate 836 in Activation of the Endoribonuclease Activity of Ire1.Expressed phosphorylase b kinase and its alphagammadelta subcomplex as regulatory models for the rabbit skeletal muscle holoenzymePhenformin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na+ transport across H441 lung cells.Activation of Dictyostelium myosin light chain kinase A by phosphorylation of Thr166.Influence of key residues on the reaction mechanism of the cAMP-dependent protein kinase.Electrostatic changes in phosphorylase kinase induced by its obligatory allosteric activator Ca2+Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides.Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface.Structural basis of constitutive activity and a unique nucleotide binding mode of human Pim-1 kinase.
P2860
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P2860
Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product
description
1995 nî lūn-bûn
@nan
1995 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Two structures of the catalyti ...... substrate analogue and product
@ast
Two structures of the catalyti ...... substrate analogue and product
@en
Two structures of the catalyti ...... substrate analogue and product
@nl
type
label
Two structures of the catalyti ...... substrate analogue and product
@ast
Two structures of the catalyti ...... substrate analogue and product
@en
Two structures of the catalyti ...... substrate analogue and product
@nl
prefLabel
Two structures of the catalyti ...... substrate analogue and product
@ast
Two structures of the catalyti ...... substrate analogue and product
@en
Two structures of the catalyti ...... substrate analogue and product
@nl
P50
P1433
P1476
Two structures of the catalyti ...... substrate analogue and product
@en
P2093
P304
P356
10.1016/S0969-2126(01)00180-0
P407
P577
1995-05-01T00:00:00Z