Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125
about
Structural and mechanistic insights into Mps1 kinase activationSmall-molecule kinase inhibitors provide insight into Mps1 cell cycle functionScaffold-Focused Virtual Screening: Prospective Application to the Discovery of TTK InhibitorsStructure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistanceStructure-Based Design of Orally Bioavailable 1 H -Pyrrolo[3,2- c ]pyridine Inhibitors of Mitotic Kinase Monopolar Spindle 1 (MPS1)Structural and functional characterization of the protein kinase Mps1 in Arabidopsis thalianaEfficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex.The MPS1 family of protein kinases.Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment.Anthrapyrazolone analogues intercept inflammatory JNK signals to moderate endotoxin induced septic shock.Mps1 (Monopolar Spindle 1) Protein Inhibition Affects Cellular Growth and Pro-Embryogenic Masses Morphology in Embryogenic Cultures of Araucaria angustifolia (Araucariaceae).Centrin 3 is an inhibitor of centrosomal Mps1 and antagonizes centrin 2 function.Selective killing of p53-deficient cancer cells by SP600125.On the molecular mechanisms of mitotic kinase activation.Mitosis as an anti-cancer drug target.KinView: a visual comparative sequence analysis tool for integrated kinome research.The hunt for antimitotic agents: an overview of structure-based design strategies.Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformationMechanisms of Mitotic Kinase Regulation: A Structural Perspective.Rigorous determination of the stoichiometry of protein phosphorylation using mass spectrometry.Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint.Reversine inhibits Colon Carcinoma Cell Migration by Targeting JNK1
P2860
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P2860
Crystal structure of the catalytic domain of the mitotic checkpoint kinase Mps1 in complex with SP600125
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Crystal structure of the catal ...... Mps1 in complex with SP600125
@ast
Crystal structure of the catal ...... Mps1 in complex with SP600125
@en
Crystal structure of the catal ...... Mps1 in complex with SP600125
@nl
type
label
Crystal structure of the catal ...... Mps1 in complex with SP600125
@ast
Crystal structure of the catal ...... Mps1 in complex with SP600125
@en
Crystal structure of the catal ...... Mps1 in complex with SP600125
@nl
prefLabel
Crystal structure of the catal ...... Mps1 in complex with SP600125
@ast
Crystal structure of the catal ...... Mps1 in complex with SP600125
@en
Crystal structure of the catal ...... Mps1 in complex with SP600125
@nl
P2093
P2860
P3181
P356
P1476
Crystal structure of the catal ...... Mps1 in complex with SP600125
@en
P2093
Kenneth T Douglas
Leonard M G Chavas
Matthew L H Chu
Patrick A Eyers
P2860
P304
21495-21500
P3181
P356
10.1074/JBC.M803026200
P407
P577
2008-05-14T00:00:00Z