Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA
about
Nuclear and mitochondrial uracil-DNA glycosylases are generated by alternative splicing and transcription from different positions in the UNG geneExcision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylaseStructural basis of acyl-homoserine lactone-dependent signalingUracil DNA N-glycosylase promotes assembly of human centromere protein AStructural basis for antiactivation in bacterial quorum sensingA bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helixStructure of uracil-DNA glycosylase fromMycobacterium tuberculosis: insights into interactions with ligandsCrystal structure and functional insights into uracil-DNA glycosylase inhibition by phage 29 DNA mimic protein p56Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitorStructure of the uracil complex ofVaccinia virusuracil DNA glycosylaseQsIA disrupts LasR dimerization in antiactivation of bacterial quorum sensingStructural and biophysical analysis of interactions between cod and human uracil-DNAN-glycosylase (UNG) and UNG inhibitor (Ugi)Structural plasticity in Mycobacterium tuberculosis uracil-DNA glycosylase (MtUng) and its functional implicationsThe DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destructionEnvisioning the dynamics and flexibility of Mre11-Rad50-Nbs1 complex to decipher its roles in DNA replication and repairUracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognitionExsD inhibits expression of the Pseudomonas aeruginosa type III secretion system by disrupting ExsA self-association and DNA binding activitySuppression of intestinal polyposis in Apc(delta 716) knockout mice by an additional mutation in the cytosolic phospholipase A(2) geneAnalysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologuesMutations in active-site residues of the uracil-DNA glycosylase encoded by vaccinia virus are incompatible with virus viabilityCrystal structure of thymine DNA glycosylase conjugated to SUMO-1Probing protein structure by amino acid-specific covalent labeling and mass spectrometry.Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.Mutational analysis of arginine 276 in the leucine-loop of human uracil-DNA glycosylase.Essential amino acid residues in the single-stranded DNA-binding protein of bacteriophage T7. Identification of the dimer interface.Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2.Escherichia coli nucleoside diphosphate kinase does not act as a uracil-processing DNA repair nuclease.Macromolecular mimicryBase excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.APOBEC3G hypermutates genomic DNA and inhibits Ty1 retrotransposition in yeast.X4 and R5 HIV-1 have distinct post-entry requirements for uracil DNA glycosylase during infection of primary cells.Characterisation of the structure of ocr, the gene 0.3 protein of bacteriophage T7.Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.Vaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells.On the molecular basis of uracil recognition in DNA: comparative study of T-A versus U-A structure, dynamics and open base pair kinetics.Mutations at Arginine 276 transform human uracil-DNA glycosylase into a single-stranded DNA-specific uracil-DNA glycosylase.The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs.Characterization of the uracil-DNA glycosylase activity of Epstein-Barr virus BKRF3 and its role in lytic viral DNA replication.Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair.Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase
P2860
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P2860
Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA
description
1995 nî lūn-bûn
@nan
1995 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@ast
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@en
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@nl
type
label
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@ast
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@en
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@nl
prefLabel
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@ast
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@en
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@nl
P2093
P3181
P1433
P1476
Crystal structure of human ura ...... ibitor: protein mimicry of DNA
@en
P2093
P3181
P356
10.1016/0092-8674(95)90467-0
P407
P577
1995-09-08T00:00:00Z