The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. - Wikidata - wikimedia - TriplyDB

The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs.

The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs.

http://www.wikidata.org/entity/Q34980538

about

Endonuclease V cleaves at inosines in RNA Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif.The current state of eukaryotic DNA base damage and repair DNA glycosylases: in DNA repair and beyond Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil DNA methylation, its mediators and genome integrity Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites Polymorphisms in TDG and MGMT genes - epidemiological and functional study in lung cancer patients from Poland MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs Correlated Mutation in the Evolution of Catalysis in Uracil DNA Glycosylase Superfamily Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity.Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes.Methylation-independent DNA binding modulates specificity of Repressor of Silencing 1 (ROS1) and facilitates demethylation in long substrates.Cytidine deaminases: AIDing DNA demethylation?Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites.DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.Role of the Arabidopsis DNA glycosylase/lyase ROS1 in active DNA demethylation.Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.Phylogenomic analysis of the uracil-DNA glycosylase superfamily Crossovers are associated with mutation and biased gene conversion at recombination hotspots Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase.Base excision repair and design of small molecule inhibitors of human DNA polymerase β.Cell cycle regulation as a mechanism for functional separation of the apparently redundant uracil DNA glycosylases TDG and UNG2.Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase Dependence of antibody gene diversification on uracil excision.7,8-Dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases.Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53

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The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs.

http://www.wikidata.org/entity/Q34980538

description

2003 nî lūn-bûn

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2003 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2003 թվականի մայիսին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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name

The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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type

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

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Nucleic Acids Research

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The versatile thymine DNA-glyc ...... a and fission yeast orthologs.

@en

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Josef Jiricny

http://www.w3.org/2001/XMLSchema#string

Marc Bentele

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Ulrike Hardeland

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P2860

Identification and characterization of a family of mammalian methyl-CpG binding proteins

hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup

Crystal structure of a G:T/U mismatch-specific DNA glycosylase: mismatch recognition by complementary-strand interactions

Post-replicative base excision repair in replication foci

Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates

Crystal structure of a thwarted mismatch glycosylase DNA repair complex

Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA

The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

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2261-2271

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scholarly article

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10.1093/NAR/GKG344

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9

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31

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12711670

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154230

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