Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution
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Pyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon, Pyrococcus furiosus, functions as a CoA-dependent pyruvate decarboxylaseStructural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenaseThe crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediateGlyoxylate carboligase lacks the canonical active site glutamate of thiamine-dependent enzymesStructural studies of thiamin monophosphate kinase in complex with substrates and productsStructural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis ,FrsA functions as a cofactor-independent decarboxylase to control metabolic fluxPerturbation of the Monomer–Monomer Interfaces of the Benzoylformate Decarboxylase TetramerHigh resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylasesCyclohexane-1,2-dione hydrolase from denitrifying Azoarcus sp. strain 22Lin, a novel member of the thiamine diphosphate enzyme familyEvidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate bindingCatalytically active filaments - pyruvate decarboxylase from Neurospora crassa. pH-controlled oligomer structure and catalytic function.Amino acids allosterically regulate the thiamine diphosphate-dependent alpha-keto acid decarboxylase from Mycobacterium tuberculosis.Examination of donor substrate conversion in yeast transketolase.Functional anthology of intrinsic disorder. 3. Ligands, post-translational modifications, and diseases associated with intrinsically disordered proteins.Roles of active site and novel K+ ion-binding site residues in human mitochondrial branched-chain alpha-ketoacid decarboxylase/dehydrogenase.Cloning and characterization of two pyruvate decarboxylase genes from Pichia stipitis CBS 6054.Interplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids.The phosphonopyruvate decarboxylase from Bacteroides fragilis.Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase.The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymesExperimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observationsReaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.Investigation of the cofactor-binding site of Zymomonas mobilis pyruvate decarboxylase by site-directed mutagenesisAutoregulation of yeast pyruvate decarboxylase gene expression requires the enzyme but not its catalytic activity.Identification of charge transfer transitions related to thiamin-bound intermediates on enzymes provides a plethora of signatures useful in mechanistic studies.Acetohydroxyacid synthases: evolution, structure, and function.Identification, cloning, and characterization of a Lactococcus lactis branched-chain alpha-keto acid decarboxylase involved in flavor formation.Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamateThiN as a Versatile Domain of Transcriptional Repressors and Catalytic Enzymes of Thiamine Biosynthesis.Aspartate-27 and glutamate-473 are involved in catalysis by Zymomonas mobilis pyruvate decarboxylase.The role of residues glutamate-50 and phenylalanine-496 in Zymomonas mobilis pyruvate decarboxylaseEffects of deletions at the C-terminus of tobacco acetohydroxyacid synthase on the enzyme activity and cofactor bindingBifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4'-aminopyrimidine ring when various intermediates occupy the active sites during the catalysis of yeast pyruvate decarboxylase.Crystal structure of a ring-cleaving cyclohexane-1,2-dione hydrolase, a novel member of the thiamine diphosphate enzyme family.Interaction of component enzymes with the peripheral subunit-binding domain of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus: stoichiometry and specificity in self-assembly.Purification and crystallization of benzoylformate decarboxylase.Gold(I)-catalysed synthesis of a furan analogue of thiamine pyrophosphate.Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase.
P2860
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P2860
Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4-A resolution
description
1993 nî lūn-bûn
@nan
1993 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@ast
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@en
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@nl
type
label
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@ast
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@en
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@nl
prefLabel
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@ast
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@en
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@nl
P2093
P356
P1433
P1476
Catalytic centers in the thiam ...... arboxylase at 2.4-A resolution
@en
P2093
P304
P356
10.1021/BI00075A008
P407
P577
1993-06-22T00:00:00Z