Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution
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Determination of domain structure of proteins from X-ray solution scatteringGlobal rigid body modeling of macromolecular complexes against small-angle scattering dataPyruvate ferredoxin oxidoreductase from the hyperthermophilic archaeon, Pyrococcus furiosus, functions as a CoA-dependent pyruvate decarboxylaseCrystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acidThe crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediateCrystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathwayThe crystal structure of phenylpyruvate decarboxylase from Azospirillum brasilense at 1.5 A resolution. Implications for its catalytic and regulatory mechanismCovalently Bound Substrate at the Regulatory Site of Yeast Pyruvate Decarboxylases Triggers Allosteric Enzyme ActivationStructural Insights into the Prereaction State of Pyruvate Decarboxylase from Zymomonas mobilis ,Double Duty for a Conserved Glutamate in Pyruvate Decarboxylase: Evidence of the Participation in Stereoelectronically Controlled Decarboxylation and in Protonation of the Nascent Carbanion/Enamine Intermediate,FrsA functions as a cofactor-independent decarboxylase to control metabolic fluxPerturbation of the Monomer–Monomer Interfaces of the Benzoylformate Decarboxylase TetramerA dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)High resolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylasesComparison of pyruvate decarboxylases from Saccharomyces cerevisiae and Komagataella pastoris (Pichia pastoris).Characterization of a thiamin diphosphate-dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae.Enhanced production of 2,3-butanediol by engineered Saccharomyces cerevisiae through fine-tuning of pyruvate decarboxylase and NADH oxidase activitiesAmino acids allosterically regulate the thiamine diphosphate-dependent alpha-keto acid decarboxylase from Mycobacterium tuberculosis.The crystal structure of pyruvate decarboxylase from Kluyveromyces lactis. Implications for the substrate activation mechanism of this enzyme.Examination of donor substrate conversion in yeast transketolase.Structural basis for activation of the thiamin diphosphate-dependent enzyme oxalyl-CoA decarboxylase by adenosine diphosphate.Structural trees for protein superfamilies.Roles of active site and novel K+ ion-binding site residues in human mitochondrial branched-chain alpha-ketoacid decarboxylase/dehydrogenase.Cloning and characterization of two pyruvate decarboxylase genes from Pichia stipitis CBS 6054.Improving the carboligase activity of benzoylformate decarboxylase from Pseudomonas putida by a combination of directed evolution and site-directed mutagenesis.A comparative genomics approach to understanding the biosynthesis of the sunscreen scytonemin in cyanobacteriaDecarboxylation of pyruvate to acetaldehyde for ethanol production by hyperthermophilesInterplay of organic and biological chemistry in understanding coenzyme mechanisms: example of thiamin diphosphate-dependent decarboxylations of 2-oxo acids.Structure and functional characterization of pyruvate decarboxylase from Gluconacetobacter diazotrophicus.Modeling of pyruvate decarboxylases from ethanol producing bacteria.The phosphonopyruvate decarboxylase from Bacteroides fragilis.Identification of the catalytic glutamate in the E1 component of human pyruvate dehydrogenase.The 1',4'-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymesExperimental observation of thiamin diphosphate-bound intermediates on enzymes and mechanistic information derived from these observationsComputer simulations of enzyme catalysis: finding out what has been optimized by evolution.Isotopic and other studies on the molecular origins of substrate regulation of some pyruvate decarboxylases: a reconsideration.Electronic and nuclear magnetic resonance spectroscopic features of the 1',4'-iminopyrimidine tautomeric form of thiamin diphosphate, a novel intermediate on enzymes requiring this coenzymeReaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps.Using site-saturation mutagenesis to explore mechanism and substrate specificity in thiamin diphosphate-dependent enzymes.Catalysis in Enzymatic Decarboxylations: Comparison of Selected Cofactor-dependent and Cofactor-independent Examples.
P2860
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P2860
Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@ast
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@en
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@nl
type
label
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@ast
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@en
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@nl
prefLabel
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@ast
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@en
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@nl
P2093
P356
P1476
Crystal structure of the thiam ...... cerevisiae at 2.3 A resolution
@en
P2093
B Farrenkopf
S Swaminathan
P304
P356
10.1006/JMBI.1996.0111
P407
P577
1996-03-01T00:00:00Z