X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
about
Multimodular penicillin-binding proteins: an enigmatic family of orthologs and paralogsCrystal structures of penicillin-binding protein 2 from penicillin-susceptible and -resistant strains of Neisseria gonorrhoeae reveal an unexpectedly subtle mechanism for antibiotic resistanceSystematic association of genes to phenotypes by genome and literature miningGlycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New AntibacterialsThe crystal structure of a penicilloyl-serine transferase of intermediate penicillin sensitivity. The DD-transpeptidase of streptomyces K15Crystal structure of a deacylation-defective mutant of penicillin-binding protein 5 at 2.3-A resolutionA 1.2-A snapshot of the final step of bacterial cell wall biosynthesisCrystal structure of PBP2x from a highly penicillin-resistant Streptococcus pneumoniae clinical isolate: a mosaic framework containing 83 mutationsA PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibioticsCrystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for Its High Antimicrobial ActivityCrystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniaeUnusual Conformation of the SxN Motif in the Crystal Structure of Penicillin-Binding Protein A from Mycobacterium tuberculosisCrystal Structures of Penicillin-Binding Protein 3 from Pseudomonas aeruginosa: Comparison of Native and Antibiotic-Bound FormsX-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureusCrystal Structure of Penicillin-Binding Protein 3 (PBP3) from Escherichia coliPenicillin-binding proteins and beta-lactam resistanceMolecular dynamics simulation of the complex PBP-2x with drug cefuroxime to explore the drug resistance mechanism of Streptococcus suis R61Evidence from artificial septal targeting and site-directed mutagenesis that residues in the extracytoplasmic β domain of DivIB mediate its interaction with the divisomal transpeptidase PBP 2BCytokinesis in bacteriaKinship and diversification of bacterial penicillin-binding proteins and beta-lactamases.Lack of cell wall peptidoglycan versus penicillin sensitivity: new insights into the chlamydial anomaly.Active site restructuring regulates ligand recognition in class A penicillin-binding proteinsAssociation of amino acid substitutions in penicillin-binding protein 3 with beta-lactam resistance in beta-lactamase-negative ampicillin-resistant Haemophilus influenzae.Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.Evidence that CT694 is a novel Chlamydia trachomatis T3S substrate capable of functioning during invasion or early cycle development.Bacterial cell wall synthesis: new insights from localization studiesRecognition of peptidoglycan and β-lactam antibiotics by the extracellular domain of the Ser/Thr protein kinase StkP from Streptococcus pneumoniae.Genetic analysis of the cell division protein FtsI (PBP3): amino acid substitutions that impair septal localization of FtsI and recruitment of FtsN.Reconstitution of membrane protein complexes involved in pneumococcal septal cell wall assemblyMutational analysis of class A and class B penicillin-binding proteins in Streptococcus gordonii.Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faeciumThe non-penicillin-binding module of the tripartite penicillin-binding protein 3 of Escherichia coli is required for folding and/or stability of the penicillin-binding module and the membrane-anchoring module confers cell septation activity on the fCloning and characterization of the ponA gene encoding penicillin-binding protein 1 from Neisseria gonorrhoeae and Neisseria meningitidisTopographical and functional investigation of Escherichia coli penicillin-binding protein 1b by alanine stretch scanning mutagenesis.Whole Genome Sequencing of 39 Invasive Streptococcus pneumoniae Sequence Type 199 Isolates Revealed Switches from Serotype 19A to 15BImpact of specific pbp5 mutations on expression of beta-lactam resistance in Enterococcus faecium.Antimicrobial resistance in Haemophilus influenzaeIdentification of a structural determinant for resistance to beta-lactam antibiotics in Gram-positive bacteria.Characterization of a serine/threonine kinase involved in virulence of Staphylococcus aureus.Evidence for a dual role of PBP1 in the cell division and cell separation of Staphylococcus aureus.
P2860
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P2860
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@ast
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@en
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@nl
type
label
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@ast
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@en
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@nl
prefLabel
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@ast
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@en
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@nl
P2093
P2860
P356
P1476
X-ray structure of Streptococcus pneumoniae PBP2x, a primary penicillin target enzyme
@en
P2093
P2860
P356
10.1038/NSB0396-284
P577
1996-03-01T00:00:00Z