Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography - Wikidata - wikimedia - TriplyDB

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

http://www.wikidata.org/entity/Q27734359

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Interferon-kappa, a novel type I interferon expressed in human keratinocytes Intermolecular Interactions in a 44 kDa Interferon−Receptor Complex Detected by Asymmetric Reverse-Protonation and Two-Dimensional NOESY Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation.The crystal structure of human interferon beta at 2.2-A resolution Roles of Zinc Signaling in the Immune System Therapeutic alpha-interferons protein: structure, production, and biosimilar.Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes.Effects of localized interactions and surface properties on stability of protein-based therapeutics.Antagonist peptides of human interferon-alpha2b isolated from phage display library inhibit interferon induced antiviral activity.Identification of antiviral mimetic peptides with interferon alpha-2b-like activity from a random peptide library using a novel functional biopanning method.Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells.Zinc is a potent and specific inhibitor of IFN-λ3 signalling.The human interferon alpha species and receptors.Pegylating IFNs at his-34 improves the in vitro antiviral activity through the JAK/STAT pathway.Blood micronutrient, oxidative stress, and viral load in patients with chronic hepatitis C.Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent.Interleukin-6: structure-function relationships.Determination of the human type I interferon receptor binding site on human interferon-alpha2 by cross saturation and an NMR-based model of the complex.Human interferon alpha-2b: a therapeutic protein for cancer treatment IFNA2: The prototypic human alpha interferon.Lambda Interferons: New Cytokines with Old Functions.NMR mapping of the IFNAR1-EC binding site on IFNalpha2 reveals allosteric changes in the IFNAR2-EC binding site.Metal ions guided self-assembly of therapeutic proteins for controllable release: from random to ordered aggregation.Development of a cultivation process for the enhancement of human interferon alpha 2b production in the oleaginous yeast, Yarrowia lipolytica.Site of pegylation and polyethylene glycol molecule size attenuate interferon-alpha antiviral and antiproliferative activities through the JAK/STAT signaling pathway.Characterization of N-terminal interferon tau mutants: P26L affords enhanced activity and lack of toxicity.New structural and functional aspects of the type I interferon-receptor interaction revealed by comprehensive mutational analysis of the binding interface.Structural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab.Heterologous expression, immunochemical and computational analysis of recombinant human interferon alpha 2b.The EM structure of a type I interferon-receptor complex reveals a novel mechanism for cytokine signaling.Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-interferon antibody fragment and human interferon alpha-2A.A panel of synthetic antibodies that selectively recognize and antagonize members of the interferon alpha family.Characterization of a soluble ternary complex formed between human interferon-beta-1a and its receptor chains.A Potent In Vivo Antitumor Efficacy of Novel Recombinant Type I Interferon.Zinc supplementation enhances the response to interferon therapy in patients with chronic hepatitis C.Construction, expression and characterization of human interferon alpha2b-(G4S)n-thymosin alpha1 fusion proteins in Pichia pastoris.Production of bioactive liver-targeting interferon Mu-IFN-CSP by soluble prokaryotic expression.Characterization of interferon-alpha 13, a novel constitutive murine interferon-alpha subtype.

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P2860

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

http://www.wikidata.org/entity/Q27734359

description

1996 nî lūn-bûn

@nan

1996 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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name

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@ast

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@en

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

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type

label

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@ast

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@en

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@nl

prefLabel

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@ast

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

@en

Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

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Zinc mediated dimer of human interferon-alpha 2b revealed by X-ray crystallography

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A Hruza

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L J Walter

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M R Walter

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P Reichert

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T L Nagabhushan

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scholarly article

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